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X Demographics
Mendeley readers
| Title |
Deep brain stimulation of the basolateral amygdala for treatment-refractory combat post-traumatic stress disorder (PTSD): study protocol for a pilot randomized controlled trial with blinded, staggered onset of stimulation
|
|---|---|
| Published in |
Trials, September 2014
|
| DOI | 10.1186/1745-6215-15-356 |
| Pubmed ID | |
| Authors |
Ralph J Koek, Jean-Philippe Langevin, Scott E Krahl, Hovsep J Kosoyan, Holly N Schwartz, James WY Chen, Rebecca Melrose, Mark J Mandelkern, David Sultzer |
| Abstract |
Combat post-traumatic stress disorder (PTSD) involves significant suffering, impairments in social and occupational functioning, substance use and medical comorbidity, and increased mortality from suicide and other causes. Many veterans continue to suffer despite current treatments. Deep brain stimulation (DBS) has shown promise in refractory movement disorders, depression and obsessive-compulsive disorder, with deep brain targets chosen by integration of clinical and neuroimaging literature. The basolateral amygdala (BLn) is an optimal target for high-frequency DBS in PTSD based on neurocircuitry findings from a variety of perspectives. DBS of the BLn was validated in a rat model of PTSD by our group, and limited data from humans support the potential safety and effectiveness of BLn DBS. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 2 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Practitioners (doctors, other healthcare professionals) | 1 | 50% |
| Members of the public | 1 | 50% |
Mendeley readers
The data shown below were compiled from readership statistics for 343 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | <1% |
| China | 1 | <1% |
| Australia | 1 | <1% |
| Unknown | 340 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 57 | 17% |
| Student > Bachelor | 45 | 13% |
| Researcher | 40 | 12% |
| Student > Master | 35 | 10% |
| Student > Doctoral Student | 24 | 7% |
| Other | 69 | 20% |
| Unknown | 73 | 21% |
| Readers by discipline | Count | As % |
|---|---|---|
| Psychology | 59 | 17% |
| Medicine and Dentistry | 58 | 17% |
| Neuroscience | 39 | 11% |
| Agricultural and Biological Sciences | 22 | 6% |
| Nursing and Health Professions | 15 | 4% |
| Other | 53 | 15% |
| Unknown | 97 | 28% |