Title |
Poor maternal nutrition inhibits muscle development in ovine offspring
|
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Published in |
Journal of Animal Science and Biotechnology, September 2014
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DOI | 10.1186/2049-1891-5-43 |
Pubmed ID | |
Authors |
Sarah A Reed, Joseline S Raja, Maria L Hoffman, Steven A Zinn, Kristen E Govoni |
Abstract |
Maternal over and restricted nutrition has negative consequences on the muscle of offspring by reducing muscle fiber number and altering regulators of muscle growth. To determine if over and restricted maternal nutrition affected muscle growth and gene and protein expression in offspring, 36 pregnant ewes were fed 60%, 100% or 140% of National Research Council requirements from d 31 ± 1.3 of gestation until parturition. Lambs from control-fed (CON), restricted-fed (RES) or over-fed (OVER) ewes were necropsied within 1 d of birth (n = 18) or maintained on a control diet for 3 mo (n = 15). Semitendinosus muscle was collected for immunohistochemistry, and protein and gene expression analysis. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 48 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 9 | 19% |
Student > Ph. D. Student | 7 | 15% |
Student > Doctoral Student | 5 | 10% |
Student > Bachelor | 4 | 8% |
Other | 3 | 6% |
Other | 6 | 13% |
Unknown | 14 | 29% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 21 | 44% |
Veterinary Science and Veterinary Medicine | 4 | 8% |
Biochemistry, Genetics and Molecular Biology | 3 | 6% |
Medicine and Dentistry | 2 | 4% |
Nursing and Health Professions | 1 | 2% |
Other | 2 | 4% |
Unknown | 15 | 31% |