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Distribution of bla OXA-23, ISAba, Aminoglycosides resistant genes among burned

Overview of attention for article published in Annals of Clinical Microbiology and Antimicrobials, September 2014
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Title
Distribution of bla OXA-23, ISAba, Aminoglycosides resistant genes among burned & ICU patients in Tehran and Sari, Iran
Published in
Annals of Clinical Microbiology and Antimicrobials, September 2014
DOI 10.1186/s12941-014-0038-0
Pubmed ID
Authors

Mohtaram Nasrolahei, Bahador Zahedi, Abbas Bahador, Hossein Saghi, Soudeh Kholdi, Neda Jalalvand, Davoud Esmaeili

Abstract

BackgroundMultidrug resistant strains of Acinetobacter baumannii (MDR-AB) have emerged as alarming nosocomial pathogens among patients admitted to Intensive Care Unit and burned patients. The aim of this study was to determine the susceptibility of A. baumannii isolates, the carbapenems resistance patterns bla OXA-23 and also IS Aba elements of A. baumannii isolates among burned and ICU patients in Tehran and Sari, Iran.MethodsIn this study, 100 A. baumannii isolates from burned and ICU patients in Tehran and Sari (Iran) during 2013 were tested for determination of antimicrobials susceptibility by the disc-diffusion method on Mueller Hinton agar recommended by the guidelines of Clinical and Laboratory Standards Institute (CLSI), and frequency blaOXA-23 carbapenemase genes, and insertion elements IS Aba genes were studied by PCR method.ResultsThe highest rates of susceptibility were observed with Colistin (88.7%), Tigecycline (82.2%), Imipenem (67%) and ISAba (32.2%). The extensively drug-resistance and pan drug-resistance were observed in 37.1% and 8.1% isolates, respectively.Results indicated among isolates resistant to Aminoglycoside and Carbapenem, the highest resistance was observed to Streptomycin (90%) ¿ and the most sensitivity was to Imipenem (67%).ConclusionsThis is the most study that attempted to detect Acinetobacter baumanii the insertion elements IS Aba , bla OXA-23 and aminoglycosides resistance in MDR-AB isolates from burned and ICU patients in Iran. In a timely manner, antimicrobial resistance surveillance and strict infection control strategies are still lacking in burn ward and ICU in Iran, despite the alarming emergence of MDR-AB strains, particularly among those isolates that are not susceptible to Colistin. The results of this study are consistent with a recent report in which a number of combinations exhibited potent activity against Multidrug resistant strains of A. baumannii (MDR-AB).

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 56 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
India 1 2%
Unknown 55 98%

Demographic breakdown

Readers by professional status Count As %
Student > Master 10 18%
Researcher 7 13%
Student > Postgraduate 5 9%
Other 5 9%
Student > Doctoral Student 4 7%
Other 11 20%
Unknown 14 25%
Readers by discipline Count As %
Medicine and Dentistry 13 23%
Agricultural and Biological Sciences 7 13%
Environmental Science 5 9%
Pharmacology, Toxicology and Pharmaceutical Science 4 7%
Immunology and Microbiology 3 5%
Other 7 13%
Unknown 17 30%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 October 2015.
All research outputs
#17,727,479
of 22,764,165 outputs
Outputs from Annals of Clinical Microbiology and Antimicrobials
#394
of 606 outputs
Outputs of similar age
#169,548
of 252,140 outputs
Outputs of similar age from Annals of Clinical Microbiology and Antimicrobials
#5
of 11 outputs
Altmetric has tracked 22,764,165 research outputs across all sources so far. This one is in the 19th percentile – i.e., 19% of other outputs scored the same or lower than it.
So far Altmetric has tracked 606 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.3. This one is in the 24th percentile – i.e., 24% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 252,140 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 28th percentile – i.e., 28% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 11 others from the same source and published within six weeks on either side of this one. This one is in the 45th percentile – i.e., 45% of its contemporaries scored the same or lower than it.