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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Omega 3 fatty acids chemosensitize multidrug resistant colon cancer cells by down-regulating cholesterol synthesis and altering detergent resistant membranes composition
|
|---|---|
| Published in |
Molecular Cancer, November 2013
|
| DOI | 10.1186/1476-4598-12-137 |
| Pubmed ID | |
| Authors |
Giada Gelsomino, Paola A Corsetto, Ivana Campia, Gigliola Montorfano, Joanna Kopecka, Barbara Castella, Elena Gazzano, Dario Ghigo, Angela M Rizzo, Chiara Riganti |
| Abstract |
The activity of P-glycoprotein (Pgp) and multidrug resistance related protein 1 (MRP1), two membrane transporters involved in multidrug resistance of colon cancer, is increased by high amounts of cholesterol in plasma membrane and detergent resistant membranes (DRMs). It has never been investigated whether omega 3 polyunsatured fatty acids (PUFAs), which modulate cholesterol homeostasis in dyslipidemic syndromes and have chemopreventive effects in colon cancer, may affect the response to chemotherapy in multidrug resistant (MDR) tumors. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Central African Republic | 1 | 50% |
| Unknown | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 68 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Canada | 1 | 1% |
| Unknown | 67 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 11 | 16% |
| Student > Bachelor | 10 | 15% |
| Student > Ph. D. Student | 8 | 12% |
| Student > Master | 7 | 10% |
| Other | 4 | 6% |
| Other | 14 | 21% |
| Unknown | 14 | 21% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 14 | 21% |
| Agricultural and Biological Sciences | 12 | 18% |
| Medicine and Dentistry | 11 | 16% |
| Pharmacology, Toxicology and Pharmaceutical Science | 5 | 7% |
| Nursing and Health Professions | 5 | 7% |
| Other | 5 | 7% |
| Unknown | 16 | 24% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 September 2014.
All research outputs
#14,658,791
of 22,764,165 outputs
Outputs from Molecular Cancer
#966
of 1,719 outputs
Outputs of similar age
#123,956
of 212,478 outputs
Outputs of similar age from Molecular Cancer
#15
of 25 outputs
Altmetric has tracked 22,764,165 research outputs across all sources so far. This one is in the 35th percentile – i.e., 35% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,719 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.7. This one is in the 43rd percentile – i.e., 43% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 212,478 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 40th percentile – i.e., 40% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 25 others from the same source and published within six weeks on either side of this one. This one is in the 40th percentile – i.e., 40% of its contemporaries scored the same or lower than it.