Title |
Proton radiotherapy for pediatric tumors: review of first clinical results
|
---|---|
Published in |
Italian Journal of Pediatrics, September 2014
|
DOI | 10.1186/s13052-014-0074-6 |
Pubmed ID | |
Authors |
Barbara Rombi, Sabina Vennarini, Lorenzo Vinante, Daniele Ravanelli, Maurizio Amichetti |
Abstract |
Radiation therapy is a part of multidisciplinary management of several childhood cancers. Proton therapy is a new method of irradiation, which uses protons instead of photons. Proton radiation has been used safely and effectively for medulloblastoma, primitive neuro-ectodermal tumors, craniopharyngioma, ependymoma, germ cell intracranial tumors, low-grade glioma, retinoblastoma, rhabdomyosarcoma and other soft tissue sarcomas, Ewing¿s sarcoma and other bone sarcomas. Moreover, other possible applications are emerging, in particular for lymphoma and neuroblastoma. Although both photon and proton techniques allow similar target volume coverage, the main advantage of proton radiation therapy is to sparing of intermediate-to-low-dose to healthy tissues. This characteristic could translate into clinical reduction of side effects, including a lower risk for secondary cancers. The following review presents the state of the art of proton therapy in the treatment of pediatric malignancies. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 2 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 101 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 15 | 15% |
Student > Bachelor | 13 | 13% |
Researcher | 11 | 11% |
Other | 9 | 9% |
Student > Master | 9 | 9% |
Other | 20 | 20% |
Unknown | 24 | 24% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 42 | 42% |
Physics and Astronomy | 9 | 9% |
Nursing and Health Professions | 6 | 6% |
Psychology | 5 | 5% |
Agricultural and Biological Sciences | 3 | 3% |
Other | 10 | 10% |
Unknown | 26 | 26% |