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Risk determination and prevention of breast cancer

Overview of attention for article published in Breast Cancer Research, September 2014
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (96th percentile)
  • High Attention Score compared to outputs of the same age and source (97th percentile)

Mentioned by

news
3 news outlets
blogs
1 blog
twitter
25 tweeters
weibo
2 weibo users
facebook
2 Facebook pages

Citations

dimensions_citation
244 Dimensions

Readers on

mendeley
753 Mendeley
citeulike
3 CiteULike
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Title
Risk determination and prevention of breast cancer
Published in
Breast Cancer Research, September 2014
DOI 10.1186/s13058-014-0446-2
Pubmed ID
Authors

Anthony Howell, Annie S Anderson, Robert B Clarke, Stephen W Duffy, D Gareth Evans, Montserat Garcia-Closas, Andy J Gescher, Timothy J Key, John M Saxton, Michelle N Harvie

Abstract

Breast cancer is an increasing public health problem. Substantial advances have been made in the treatment of breast cancer, but the introduction of methods to predict women at elevated risk and prevent the disease has been less successful. Here, we summarize recent data on newer approaches to risk prediction, available approaches to prevention, how new approaches may be made, and the difficult problem of using what we already know to prevent breast cancer in populations. During 2012, the Breast Cancer Campaign facilitated a series of workshops, each covering a specialty area of breast cancer to identify gaps in our knowledge. The risk-and-prevention panel involved in this exercise was asked to expand and update its report and review recent relevant peer-reviewed literature. The enlarged position paper presented here highlights the key gaps in risk-and-prevention research that were identified, together with recommendations for action. The panel estimated from the relevant literature that potentially 50% of breast cancer could be prevented in the subgroup of women at high and moderate risk of breast cancer by using current chemoprevention (tamoxifen, raloxifene, exemestane, and anastrozole) and that, in all women, lifestyle measures, including weight control, exercise, and moderating alcohol intake, could reduce breast cancer risk by about 30%. Risk may be estimated by standard models potentially with the addition of, for example, mammographic density and appropriate single-nucleotide polymorphisms. This review expands on four areas: (a) the prediction of breast cancer risk, (b) the evidence for the effectiveness of preventive therapy and lifestyle approaches to prevention, (c) how understanding the biology of the breast may lead to new targets for prevention, and (d) a summary of published guidelines for preventive approaches and measures required for their implementation. We hope that efforts to fill these and other gaps will lead to considerable advances in our efforts to predict risk and prevent breast cancer over the next 10 years.

Twitter Demographics

Twitter Demographics

The data shown below were collected from the profiles of 25 tweeters who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 753 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 3 <1%
Brazil 2 <1%
Brunei Darussalam 1 <1%
Portugal 1 <1%
Germany 1 <1%
Spain 1 <1%
Unknown 744 99%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 128 17%
Student > Master 123 16%
Student > Ph. D. Student 78 10%
Researcher 61 8%
Student > Postgraduate 51 7%
Other 147 20%
Unknown 165 22%
Readers by discipline Count As %
Medicine and Dentistry 182 24%
Biochemistry, Genetics and Molecular Biology 97 13%
Agricultural and Biological Sciences 70 9%
Nursing and Health Professions 58 8%
Pharmacology, Toxicology and Pharmaceutical Science 29 4%
Other 133 18%
Unknown 184 24%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 52. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 October 2022.
All research outputs
#750,869
of 24,041,016 outputs
Outputs from Breast Cancer Research
#60
of 1,972 outputs
Outputs of similar age
#8,242
of 256,844 outputs
Outputs of similar age from Breast Cancer Research
#2
of 45 outputs
Altmetric has tracked 24,041,016 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 96th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,972 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 12.1. This one has done particularly well, scoring higher than 97% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 256,844 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 96% of its contemporaries.
We're also able to compare this research output to 45 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 97% of its contemporaries.