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Mendeley readers
| Title |
Low genetic diversity in the locus encoding the Plasmodium vivax P41 protein in Colombia’s parasite population
|
|---|---|
| Published in |
Malaria Journal, September 2014
|
| DOI | 10.1186/1475-2875-13-388 |
| Pubmed ID | |
| Authors |
Johanna Forero-Rodríguez, Diego Garzón-Ospina, Manuel A Patarroyo |
| Abstract |
The development of malaria vaccine has been hindered by the allele-specific responses produced by some parasite antigens' high genetic diversity. Such antigen genetic diversity must thus be evaluated when designing a completely effective vaccine. Plasmodium falciparum P12, P38 and P41 proteins have red blood cell binding regions in the s48/45 domains and are located on merozoite surface, P41 forming a heteroduplex with P12. These three genes have been identified in Plasmodium vivax and share similar characteristics with their orthologues in Plasmodium falciparum. Plasmodium vivax pv12 and pv38 have low genetic diversity but pv41 polymorphism has not been described. |
Mendeley readers
The data shown below were compiled from readership statistics for 18 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 18 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 6 | 33% |
| Student > Bachelor | 3 | 17% |
| Researcher | 2 | 11% |
| Professor | 1 | 6% |
| Lecturer > Senior Lecturer | 1 | 6% |
| Other | 2 | 11% |
| Unknown | 3 | 17% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 6 | 33% |
| Biochemistry, Genetics and Molecular Biology | 3 | 17% |
| Agricultural and Biological Sciences | 2 | 11% |
| Computer Science | 2 | 11% |
| Immunology and Microbiology | 1 | 6% |
| Other | 0 | 0% |
| Unknown | 4 | 22% |