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Melatonin reduces TNF-a induced expression of MAdCAM-1 via inhibition of NF-kB.

Overview of attention for article published in BMC Gastroenterology, April 2002
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Title
Melatonin reduces TNF-a induced expression of MAdCAM-1 via inhibition of NF-kB.
Published in
BMC Gastroenterology, April 2002
DOI 10.1186/1471-230x-2-9
Pubmed ID
Authors

Makoto Sasaki, Paul Jordan, Takashi Joh, Makotoh Itoh, Michael Jenkins, Kevin Pavlick, Alireza Minagar, Steven J Alexander

Abstract

Endothelial MAdCAM-1 (mucosal addressin cell adhesion molecule-1) expression is associated with the oxidant-dependent induction and progress of inflammatory bowel disease (IBD). Melatonin, a relatively safe, potent antioxidant, has shown efficacy in several chronic injury models may limit MAdCAM-1 expression and therefore have a therapeutic use in IBD.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 47 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 2%
Spain 1 2%
Poland 1 2%
Unknown 44 94%

Demographic breakdown

Readers by professional status Count As %
Researcher 7 15%
Student > Ph. D. Student 6 13%
Professor > Associate Professor 6 13%
Student > Bachelor 5 11%
Other 4 9%
Other 12 26%
Unknown 7 15%
Readers by discipline Count As %
Medicine and Dentistry 15 32%
Agricultural and Biological Sciences 13 28%
Biochemistry, Genetics and Molecular Biology 5 11%
Immunology and Microbiology 2 4%
Pharmacology, Toxicology and Pharmaceutical Science 1 2%
Other 2 4%
Unknown 9 19%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 October 2014.
All research outputs
#20,238,443
of 22,765,347 outputs
Outputs from BMC Gastroenterology
#1,361
of 1,742 outputs
Outputs of similar age
#119,648
of 121,083 outputs
Outputs of similar age from BMC Gastroenterology
#2
of 2 outputs
Altmetric has tracked 22,765,347 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,742 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.0. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 121,083 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 2 others from the same source and published within six weeks on either side of this one.