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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Triptans and CGRP blockade – impact on the cranial vasculature
|
|---|---|
| Published in |
The Journal of Headache and Pain, October 2017
|
| DOI | 10.1186/s10194-017-0811-5 |
| Pubmed ID | |
| Authors |
Silvia Benemei, Francesca Cortese, Alejandro Labastida-Ramírez, Francesca Marchese, Lanfranco Pellesi, Michele Romoli, Anne Luise Vollesen, Christian Lampl, Messoud Ashina, On behalf of the School of Advanced Studies of the European Headache Federation (EHF-SAS) |
| Abstract |
The trigeminovascular system plays a key role in the pathophysiology of migraine. The activation of the trigeminovascular system causes release of various neurotransmitters and neuropeptides, including serotonin and calcitonin gene-related peptide (CGRP), which modulate pain transmission and vascular tone. Thirty years after discovery of agonists for serotonin 5-HT1B and 5-HT1D receptors (triptans) and less than fifteen after the proof of concept of the gepant class of CGRP receptor antagonists, we are still a long way from understanding their precise site and mode of action in migraine. The effect on cranial vasculature is relevant, because all specific anti-migraine drugs and migraine pharmacological triggers may act in perivascular space. This review reports the effects of triptans and CGRP blocking molecules on cranial vasculature in humans, focusing on their specific relevance to migraine treatment. |
X Demographics
The data shown below were collected from the profiles of 5 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 40% |
| United Kingdom | 1 | 20% |
| Unknown | 2 | 40% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 4 | 80% |
| Science communicators (journalists, bloggers, editors) | 1 | 20% |
Mendeley readers
The data shown below were compiled from readership statistics for 96 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 96 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Other | 15 | 16% |
| Student > Bachelor | 12 | 13% |
| Researcher | 11 | 11% |
| Student > Ph. D. Student | 10 | 10% |
| Professor | 5 | 5% |
| Other | 13 | 14% |
| Unknown | 30 | 31% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 26 | 27% |
| Neuroscience | 13 | 14% |
| Biochemistry, Genetics and Molecular Biology | 8 | 8% |
| Pharmacology, Toxicology and Pharmaceutical Science | 6 | 6% |
| Nursing and Health Professions | 4 | 4% |
| Other | 3 | 3% |
| Unknown | 36 | 38% |
Attention Score in Context
This research output has an Altmetric Attention Score of 13. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 December 2023.
All research outputs
#2,699,464
of 25,008,338 outputs
Outputs from The Journal of Headache and Pain
#350
of 1,509 outputs
Outputs of similar age
#50,037
of 329,950 outputs
Outputs of similar age from The Journal of Headache and Pain
#8
of 16 outputs
Altmetric has tracked 25,008,338 research outputs across all sources so far. Compared to these this one has done well and is in the 89th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,509 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 19.2. This one has done well, scoring higher than 76% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 329,950 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 84% of its contemporaries.
We're also able to compare this research output to 16 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 56% of its contemporaries.