↓ Skip to main content

Pax8 modulates the expression of Wnt4 that is necessary for the maintenance of the epithelial phenotype of thyroid cells

Overview of attention for article published in BMC Molecular and Cell Biology, September 2014
Altmetric Badge

About this Attention Score

  • Average Attention Score compared to outputs of the same age
  • Above-average Attention Score compared to outputs of the same age and source (61st percentile)

Mentioned by

twitter
2 X users

Citations

dimensions_citation
6 Dimensions

Readers on

mendeley
22 Mendeley
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
Pax8 modulates the expression of Wnt4 that is necessary for the maintenance of the epithelial phenotype of thyroid cells
Published in
BMC Molecular and Cell Biology, September 2014
DOI 10.1186/1471-2199-15-21
Pubmed ID
Authors

Maria Grazia Filippone, Tina Di Palma, Valeria Lucci, Mariastella Zannini

Abstract

The transcription factor Pax8 is expressed during thyroid development and is involved in the morphogenesis of the thyroid gland and maintenance of the differentiated phenotype. In particular, Pax8 has been shown to regulate genes that are considered markers of thyroid differentiation. Recently, the analysis of the gene expression profile of FRTL-5 differentiated thyroid cells after the silencing of Pax8 identified Wnt4 as a novel target. Like the other members of the Wnt family, Wnt4 has been implicated in several developmental processes including regulation of cell fate and patterning during embryogenesis. To date, the only evidence on Wnt4 in thyroid concerns its down-regulation necessary for the progression of thyroid epithelial tumors.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 22 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Portugal 1 5%
Unknown 21 95%

Demographic breakdown

Readers by professional status Count As %
Researcher 6 27%
Student > Master 5 23%
Student > Ph. D. Student 3 14%
Student > Bachelor 2 9%
Unspecified 1 5%
Other 2 9%
Unknown 3 14%
Readers by discipline Count As %
Agricultural and Biological Sciences 5 23%
Medicine and Dentistry 5 23%
Biochemistry, Genetics and Molecular Biology 5 23%
Unspecified 1 5%
Immunology and Microbiology 1 5%
Other 1 5%
Unknown 4 18%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 27 February 2015.
All research outputs
#16,045,990
of 25,368,786 outputs
Outputs from BMC Molecular and Cell Biology
#700
of 1,232 outputs
Outputs of similar age
#142,552
of 264,646 outputs
Outputs of similar age from BMC Molecular and Cell Biology
#7
of 21 outputs
Altmetric has tracked 25,368,786 research outputs across all sources so far. This one is in the 34th percentile – i.e., 34% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,232 research outputs from this source. They receive a mean Attention Score of 4.0. This one is in the 40th percentile – i.e., 40% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 264,646 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 43rd percentile – i.e., 43% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 21 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 61% of its contemporaries.