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Attention Score in Context
| Title |
The balance between the serum levels of IL-6 and IL-10 cytokines discriminates mild and severe acute pneumonia
|
|---|---|
| Published in |
BMC Pulmonary Medicine, December 2016
|
| DOI | 10.1186/s12890-016-0324-z |
| Pubmed ID | |
| Authors |
Rita de Cássia Coelho Moraes de Brito, Norma Lucena-Silva, Leuridan Cavalcante Torres, Carlos Feitosa Luna, Jaílson de Barros Correia, Giselia Alves Pontes da Silva |
| Abstract |
To identify markers for earlier diagnosis of severe pneumonia, we assess the correlation between serum cytokine profile of children with different pneumonia severity. In 25 hospitalized children, 7 with mild pneumonia and 18 with severe pneumonia, the serum concentration of 11 cytokines in three sampling times were dosed. Statistical analysis included parametric and non-parametric tests, Pearson correlation and ROC curve for cut-off definition of cytokines. At admission, IL-6 serum levels were high in mild or severe pneumonia, and was associated to vomiting (P = 0.019) in both groups; and also to dyspnea (P = 0.012) and white blood cell count (P = 0.045) in patients with severe pneumonia. IL-10 levels were also high in patients with pneumonia and were associated to lymphocytosis (P = 0.025). The ROC curve of the IL-6:IL-10 serum levels ratio discriminated severe pneumonia cases at admission, and persistence of infection in the third day of antibiotic therapy, with positive predictive values of 93% and 89%, respectively. The balance between IL-6 and IL-10 serum levels showed to be a more discriminative marker for severity definition and evaluation of recovery in patients with pneumonia. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 50% |
| Unknown | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 86 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 86 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 12 | 14% |
| Other | 10 | 12% |
| Student > Ph. D. Student | 10 | 12% |
| Student > Bachelor | 9 | 10% |
| Student > Doctoral Student | 6 | 7% |
| Other | 18 | 21% |
| Unknown | 21 | 24% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 27 | 31% |
| Biochemistry, Genetics and Molecular Biology | 9 | 10% |
| Agricultural and Biological Sciences | 6 | 7% |
| Immunology and Microbiology | 4 | 5% |
| Pharmacology, Toxicology and Pharmaceutical Science | 3 | 3% |
| Other | 7 | 8% |
| Unknown | 30 | 35% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 October 2017.
All research outputs
#17,917,778
of 23,005,189 outputs
Outputs from BMC Pulmonary Medicine
#1,284
of 1,949 outputs
Outputs of similar age
#288,804
of 417,352 outputs
Outputs of similar age from BMC Pulmonary Medicine
#34
of 43 outputs
Altmetric has tracked 23,005,189 research outputs across all sources so far. This one is in the 19th percentile – i.e., 19% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,949 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.4. This one is in the 27th percentile – i.e., 27% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 417,352 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 26th percentile – i.e., 26% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 43 others from the same source and published within six weeks on either side of this one. This one is in the 16th percentile – i.e., 16% of its contemporaries scored the same or lower than it.