Title |
Synovial fluid and synovial membrane mesenchymal stem cells: latest discoveries and therapeutic perspectives
|
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Published in |
Stem Cell Research & Therapy, October 2014
|
DOI | 10.1186/scrt501 |
Pubmed ID | |
Authors |
Eduardo Branco de Sousa, Priscila Ladeira Casado, Vivaldo Moura Neto, Maria Eugenia Leite Duarte, Diego Pinheiro Aguiar |
Abstract |
Mesenchymal stem cells (MSCs) have the ability to differentiate into osteoblasts, chondroblasts, adipocytes, and even myoblasts. Most studies have focused on finding MSCs in different parts of the body for medical treatment. Every joint structure, including bone, joint fat, articular cartilage, and synovium, potentially contains resident MSCs. Recently, a progenitor cell population has been found in synovial fluid and showed similarities with both bone marrow and synovial membrane MSCs. Synovial fluid MSCs have been studied in healthy persons and osteoarthritic patients in order to explore its potential for treatment of some orthopedic disorders. Here, we briefly review the current knowledge on synovial fluid MSCs, their origin, relation to some orthopedic diseases, and future applications. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Scientists | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 1 | <1% |
Korea, Republic of | 1 | <1% |
Portugal | 1 | <1% |
Denmark | 1 | <1% |
Unknown | 196 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 33 | 17% |
Student > Bachelor | 30 | 15% |
Researcher | 23 | 12% |
Student > Master | 23 | 12% |
Other | 13 | 7% |
Other | 28 | 14% |
Unknown | 50 | 25% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 40 | 20% |
Biochemistry, Genetics and Molecular Biology | 31 | 16% |
Agricultural and Biological Sciences | 26 | 13% |
Veterinary Science and Veterinary Medicine | 11 | 6% |
Engineering | 11 | 6% |
Other | 25 | 13% |
Unknown | 56 | 28% |