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Engineered fungal polyketide biosynthesis in Pichia pastoris: a potential excellent host for polyketide production

Overview of attention for article published in Microbial Cell Factories, September 2013
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Title
Engineered fungal polyketide biosynthesis in Pichia pastoris: a potential excellent host for polyketide production
Published in
Microbial Cell Factories, September 2013
DOI 10.1186/1475-2859-12-77
Pubmed ID
Authors

Limei Gao, Menghao Cai, Wei Shen, Siwei Xiao, Xiangshan Zhou, Yuanxing Zhang

Abstract

Polyketides are one of the most important classes of secondary metabolites and usually make good drugs. Currently, heterologous production of fungal polyketides for developing a high potential industrial application system with high production capacity and pharmaceutical feasibility was still at its infancy. Pichia pastoris is a highly successful system for the high production of a variety of heterologous proteins. In this work, we aim to develop a P. pastoris based in vivo fungal polyketide production system for first time and evaluate its feasibility for future industrial application.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 112 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Denmark 2 2%
Indonesia 1 <1%
Austria 1 <1%
United Kingdom 1 <1%
China 1 <1%
Japan 1 <1%
United States 1 <1%
Unknown 104 93%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 29 26%
Researcher 14 13%
Student > Master 11 10%
Student > Bachelor 11 10%
Student > Doctoral Student 6 5%
Other 22 20%
Unknown 19 17%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 31 28%
Agricultural and Biological Sciences 27 24%
Chemistry 8 7%
Chemical Engineering 6 5%
Engineering 5 4%
Other 11 10%
Unknown 24 21%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 October 2014.
All research outputs
#20,238,443
of 22,765,347 outputs
Outputs from Microbial Cell Factories
#1,359
of 1,595 outputs
Outputs of similar age
#173,096
of 197,643 outputs
Outputs of similar age from Microbial Cell Factories
#5
of 5 outputs
Altmetric has tracked 22,765,347 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,595 research outputs from this source. They receive a mean Attention Score of 4.4. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 197,643 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 5 others from the same source and published within six weeks on either side of this one.