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Mendeley readers
Title |
tigaR: integrative significance analysis of temporal differential gene expression induced by genomic abnormalities
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Published in |
BMC Bioinformatics, October 2014
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DOI | 10.1186/1471-2105-15-327 |
Pubmed ID | |
Authors |
Viktorian Miok, Saskia M Wilting, Mark A van de Wiel, Annelieke Jaspers, Paula I van Noort, Ruud H Brakenhoff, Peter JF Snijders, Renske DM Steenbergen, Wessel N van Wieringen |
Abstract |
To determine which changes in the host cell genome are crucial for cervical carcinogenesis, a longitudinal in vitro model system of HPV-transformed keratinocytes was profiled in a genome-wide manner. Four cell lines affected with either HPV16 or HPV18 were assayed at 8 sequential time points for gene expression (mRNA) and gene copy number (DNA) using high-resolution microarrays. Available methods for temporal differential expression analysis are not designed for integrative genomic studies. |
Mendeley readers
The data shown below were compiled from readership statistics for 28 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
Netherlands | 1 | 4% |
Sweden | 1 | 4% |
Unknown | 26 | 93% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 7 | 25% |
Researcher | 6 | 21% |
Student > Doctoral Student | 2 | 7% |
Professor | 2 | 7% |
Professor > Associate Professor | 2 | 7% |
Other | 3 | 11% |
Unknown | 6 | 21% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 7 | 25% |
Agricultural and Biological Sciences | 6 | 21% |
Biochemistry, Genetics and Molecular Biology | 4 | 14% |
Mathematics | 2 | 7% |
Computer Science | 2 | 7% |
Other | 1 | 4% |
Unknown | 6 | 21% |