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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Mutations in CECR1 associated with a neutrophil signature in peripheral blood
|
|---|---|
| Published in |
Pediatric Rheumatology, September 2014
|
| DOI | 10.1186/1546-0096-12-44 |
| Pubmed ID | |
| Authors |
Alexandre Belot, Evangeline Wassmer, Marinka Twilt, Jean-Christophe Lega, Leo AH Zeef, Anthony Oojageer, Paul R Kasher, Anne-Laure Mathieu, Christophe Malcus, Julie Demaret, Nicole Fabien, Sophie Collardeau-Frachon, Laura Mechtouff, Laurent Derex, Thierry Walzer, Gillian I Rice, Isabelle Durieu, Yanick J Crow |
| Abstract |
A reduction of ADA2 activity due to autosomal recessive loss of function mutations in CECR1 results in a newly described vasculopathic phenotype reminiscent of polyarteritis nodosa, with manifestations ranging from fatal systemic vasculitis with multiple strokes in children to limited cutaneous disease in middle-aged individuals. Evidence indicates that ADA2 is essential for the endothelial integrity of small vessels. However, CECR1 is not expressed, nor is the ADA2 protein detectable, in cultured human endothelial cells, thus implicating additional cell types or circulating factors in disease pathogenesis. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 89 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Denmark | 1 | 1% |
| Unknown | 88 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 15 | 17% |
| Student > Ph. D. Student | 10 | 11% |
| Student > Doctoral Student | 9 | 10% |
| Professor > Associate Professor | 7 | 8% |
| Student > Master | 7 | 8% |
| Other | 19 | 21% |
| Unknown | 22 | 25% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 35 | 39% |
| Biochemistry, Genetics and Molecular Biology | 8 | 9% |
| Immunology and Microbiology | 8 | 9% |
| Agricultural and Biological Sciences | 5 | 6% |
| Nursing and Health Professions | 1 | 1% |
| Other | 4 | 4% |
| Unknown | 28 | 31% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 October 2014.
All research outputs
#14,786,597
of 22,765,347 outputs
Outputs from Pediatric Rheumatology
#436
of 693 outputs
Outputs of similar age
#138,888
of 252,167 outputs
Outputs of similar age from Pediatric Rheumatology
#10
of 22 outputs
Altmetric has tracked 22,765,347 research outputs across all sources so far. This one is in the 32nd percentile – i.e., 32% of other outputs scored the same or lower than it.
So far Altmetric has tracked 693 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.6. This one is in the 34th percentile – i.e., 34% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 252,167 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 42nd percentile – i.e., 42% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 22 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 50% of its contemporaries.