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DNA methylation links genetics, fetal environment, and an unhealthy lifestyle to the development of type 2 diabetes

Overview of attention for article published in Clinical Epigenetics, October 2017
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Good Attention Score compared to outputs of the same age (71st percentile)
  • Good Attention Score compared to outputs of the same age and source (77th percentile)

Mentioned by

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5 X users
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2 Facebook pages
wikipedia
1 Wikipedia page

Citations

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49 Dimensions

Readers on

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140 Mendeley
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Title
DNA methylation links genetics, fetal environment, and an unhealthy lifestyle to the development of type 2 diabetes
Published in
Clinical Epigenetics, October 2017
DOI 10.1186/s13148-017-0399-2
Pubmed ID
Authors

Emma Nilsson, Charlotte Ling

Abstract

Type 2 diabetes is a complex trait with both environmental and hereditary factors contributing to the overall pathogenesis. One link between genes, environment, and disease is epigenetics influencing gene transcription and, consequently, organ function. Genome-wide studies have shown altered DNA methylation in tissues important for glucose homeostasis including pancreas, liver, skeletal muscle, and adipose tissue from subjects with type 2 diabetes compared with nondiabetic controls. Factors predisposing for type 2 diabetes including an adverse intrauterine environment, increasing age, overweight, physical inactivity, a family history of the disease, and an unhealthy diet have all shown to affect the DNA methylation pattern in target tissues for insulin resistance in humans. Epigenetics including DNA methylation may therefore improve our understanding of the type 2 diabetes pathogenesis, contribute to development of novel treatments, and be a useful tool to identify individuals at risk for developing the disease.

X Demographics

X Demographics

The data shown below were collected from the profiles of 5 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 140 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 140 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 30 21%
Student > Bachelor 21 15%
Researcher 11 8%
Student > Ph. D. Student 11 8%
Student > Postgraduate 7 5%
Other 23 16%
Unknown 37 26%
Readers by discipline Count As %
Medicine and Dentistry 34 24%
Biochemistry, Genetics and Molecular Biology 22 16%
Nursing and Health Professions 12 9%
Agricultural and Biological Sciences 7 5%
Computer Science 3 2%
Other 15 11%
Unknown 47 34%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 May 2023.
All research outputs
#6,023,895
of 24,254,113 outputs
Outputs from Clinical Epigenetics
#386
of 1,359 outputs
Outputs of similar age
#91,043
of 326,731 outputs
Outputs of similar age from Clinical Epigenetics
#7
of 27 outputs
Altmetric has tracked 24,254,113 research outputs across all sources so far. Compared to these this one has done well and is in the 75th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,359 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.8. This one has gotten more attention than average, scoring higher than 71% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 326,731 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 71% of its contemporaries.
We're also able to compare this research output to 27 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 77% of its contemporaries.