Title |
Management of pulmonary vasodilator therapy in patients with pulmonary arterial hypertension during critical illness
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Published in |
Critical Care, October 2014
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DOI | 10.1186/s13054-014-0523-z |
Pubmed ID | |
Authors |
Katie M Muzevich, Hadi Chohan, Daniel C Grinnan |
Abstract |
Pulmonary arterial hypertension (PAH) is commonly treated with pulmonary arteriolar vasodilator therapy. When a patient on PAH medication is admitted to intensive care, determining how to manage their medication during the critical illness is often complicated. There may be considerations related to the inability to take medication by mouth, related to acute renal failure or acute liver injury, related to altered mental status or delirium, or related to hypotension and bacteremia. Decisions of how to manage these medications can have a major impact on the patient's clinical course. Presently, provider experience is the major tool in navigating the decisions regarding these medications. In this review, we offer our recommendations of how to manage PAH patients with critical illness who are on PAH medications. These recommendations include how to deliver medications via feeding tubes, how to dose medications in the setting of acute renal failure or acute liver failure, and how to manage medications during hypotension or when a tunneled catheter needs to be removed. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United Kingdom | 2 | 29% |
United States | 1 | 14% |
Italy | 1 | 14% |
Kuwait | 1 | 14% |
Unknown | 2 | 29% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 4 | 57% |
Practitioners (doctors, other healthcare professionals) | 1 | 14% |
Scientists | 1 | 14% |
Science communicators (journalists, bloggers, editors) | 1 | 14% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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United States | 1 | 3% |
Unknown | 39 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
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Other | 8 | 20% |
Researcher | 7 | 18% |
Student > Postgraduate | 5 | 13% |
Student > Master | 4 | 10% |
Librarian | 3 | 8% |
Other | 8 | 20% |
Unknown | 5 | 13% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 25 | 63% |
Pharmacology, Toxicology and Pharmaceutical Science | 4 | 10% |
Agricultural and Biological Sciences | 2 | 5% |
Nursing and Health Professions | 2 | 5% |
Unknown | 7 | 18% |