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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Deletions of chromosomal regulatory boundaries are associated with congenital disease
|
|---|---|
| Published in |
Genome Biology, September 2014
|
| DOI | 10.1186/s13059-014-0423-1 |
| Pubmed ID | |
| Authors |
Jonas Ibn-Salem, Sebastian Köhler, Michael I Love, Ho-Ryun Chung, Ni Huang, Matthew E Hurles, Melissa Haendel, Nicole L Washington, Damian Smedley, Christopher J Mungall, Suzanna E Lewis, Claus-Eric Ott, Sebastian Bauer, Paul N Schofield, Stefan Mundlos, Malte Spielmann, Peter N Robinson |
| Abstract |
Recent data from genome-wide chromosome conformation capture analysis indicate that the human genome is divided into conserved megabase-sized self-interacting regions called topological domains. These topological domains form the regulatory backbone of the genome and are separated by regulatory boundary elements or barriers. Copy-number variations can potentially alter the topological domain architecture by deleting or duplicating the barriers and thereby allowing enhancers from neighboring domains to ectopically activate genes causing misexpression and disease, a mutational mechanism that has recently been termed enhancer adoption. |
X Demographics
The data shown below were collected from the profiles of 23 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 6 | 26% |
| Germany | 4 | 17% |
| France | 2 | 9% |
| Australia | 1 | 4% |
| Belgium | 1 | 4% |
| Canada | 1 | 4% |
| Unknown | 8 | 35% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 15 | 65% |
| Members of the public | 7 | 30% |
| Science communicators (journalists, bloggers, editors) | 1 | 4% |
Mendeley readers
The data shown below were compiled from readership statistics for 201 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 3 | 1% |
| United Kingdom | 2 | <1% |
| Germany | 1 | <1% |
| Switzerland | 1 | <1% |
| South Africa | 1 | <1% |
| Hungary | 1 | <1% |
| Canada | 1 | <1% |
| Italy | 1 | <1% |
| Unknown | 190 | 95% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 55 | 27% |
| Researcher | 40 | 20% |
| Student > Bachelor | 20 | 10% |
| Student > Master | 18 | 9% |
| Professor | 9 | 4% |
| Other | 25 | 12% |
| Unknown | 34 | 17% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 69 | 34% |
| Agricultural and Biological Sciences | 66 | 33% |
| Medicine and Dentistry | 12 | 6% |
| Computer Science | 7 | 3% |
| Engineering | 3 | 1% |
| Other | 7 | 3% |
| Unknown | 37 | 18% |
Attention Score in Context
This research output has an Altmetric Attention Score of 15. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 September 2020.
All research outputs
#2,469,603
of 25,402,528 outputs
Outputs from Genome Biology
#2,006
of 4,470 outputs
Outputs of similar age
#25,199
of 249,332 outputs
Outputs of similar age from Genome Biology
#27
of 105 outputs
Altmetric has tracked 25,402,528 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 90th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,470 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 27.6. This one has gotten more attention than average, scoring higher than 55% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 249,332 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 89% of its contemporaries.
We're also able to compare this research output to 105 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 75% of its contemporaries.