Title |
Atypical response to erlotinib in a patient with metastatic lung adenocarcinoma: a case report
|
---|---|
Published in |
Journal of Medical Case Reports, October 2014
|
DOI | 10.1186/1752-1947-8-335 |
Pubmed ID | |
Authors |
Linda Sakhri, Elodie Meynet, Léonie Ferrer, Augustin Pirvu, Gilbert Ferretti, Denis Moro-Sibilot |
Abstract |
Tyrosine kinase inhibitors are widely prescribed in thoracic oncology and have excellent responses as a first-line treatment for locally advanced or metastatic lung cancer with epidermal growth factor receptor mutations. The side effects of tyrosine kinase inhibitors are mostly gastrointestinal and dermatological, and are usually resolved after symptomatic treatment. However, new complications have now arisen due to increased use of these drugs. Here we report a side effect of erlotinib that has not been described previously: that is, metastatic lung tumor nodules were transformed into cysts, which ruptured the pleura and were responsible for bilateral life-threatening pneumothorax. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 13 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Other | 3 | 23% |
Student > Bachelor | 2 | 15% |
Researcher | 1 | 8% |
Student > Postgraduate | 1 | 8% |
Unknown | 6 | 46% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 4 | 31% |
Pharmacology, Toxicology and Pharmaceutical Science | 1 | 8% |
Neuroscience | 1 | 8% |
Agricultural and Biological Sciences | 1 | 8% |
Unknown | 6 | 46% |