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Atypical response to erlotinib in a patient with metastatic lung adenocarcinoma: a case report

Overview of attention for article published in Journal of Medical Case Reports, October 2014
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Title
Atypical response to erlotinib in a patient with metastatic lung adenocarcinoma: a case report
Published in
Journal of Medical Case Reports, October 2014
DOI 10.1186/1752-1947-8-335
Pubmed ID
Authors

Linda Sakhri, Elodie Meynet, Léonie Ferrer, Augustin Pirvu, Gilbert Ferretti, Denis Moro-Sibilot

Abstract

Tyrosine kinase inhibitors are widely prescribed in thoracic oncology and have excellent responses as a first-line treatment for locally advanced or metastatic lung cancer with epidermal growth factor receptor mutations. The side effects of tyrosine kinase inhibitors are mostly gastrointestinal and dermatological, and are usually resolved after symptomatic treatment. However, new complications have now arisen due to increased use of these drugs. Here we report a side effect of erlotinib that has not been described previously: that is, metastatic lung tumor nodules were transformed into cysts, which ruptured the pleura and were responsible for bilateral life-threatening pneumothorax.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 13 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 13 100%

Demographic breakdown

Readers by professional status Count As %
Other 3 23%
Student > Bachelor 2 15%
Researcher 1 8%
Student > Postgraduate 1 8%
Unknown 6 46%
Readers by discipline Count As %
Medicine and Dentistry 4 31%
Pharmacology, Toxicology and Pharmaceutical Science 1 8%
Neuroscience 1 8%
Agricultural and Biological Sciences 1 8%
Unknown 6 46%