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Mendeley readers
| Title |
The p38alpha mitogen-activated protein kinase limits the CNS proinflammatory cytokine response to systemic lipopolysaccharide, potentially through an IL-10 dependent mechanism
|
|---|---|
| Published in |
Journal of Neuroinflammation, October 2014
|
| DOI | 10.1186/s12974-014-0175-6 |
| Pubmed ID | |
| Authors |
Adam D Bachstetter, Bin Xing, Linda J Van Eldik |
| Abstract |
The p38α mitogen-activated protein kinase (MAPK) is a well-characterized intracellular kinase involved in the overproduction of proinflammatory cytokines from glia. As such, p38α appears to be a promising therapeutic target for neurodegenerative diseases associated with neuroinflammation. However, the in vivo role of p38α in cytokine production in the CNS is poorly defined, and prior work suggests that p38α may be affecting a yet to be identified negative feedback mechanism that limits the acute, injury-induced proinflammatory cytokine surge in the CNS. |
Mendeley readers
The data shown below were compiled from readership statistics for 30 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Germany | 1 | 3% |
| Unknown | 29 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 7 | 23% |
| Student > Master | 6 | 20% |
| Other | 3 | 10% |
| Student > Bachelor | 3 | 10% |
| Student > Doctoral Student | 2 | 7% |
| Other | 2 | 7% |
| Unknown | 7 | 23% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 7 | 23% |
| Neuroscience | 5 | 17% |
| Biochemistry, Genetics and Molecular Biology | 3 | 10% |
| Chemistry | 2 | 7% |
| Medicine and Dentistry | 2 | 7% |
| Other | 5 | 17% |
| Unknown | 6 | 20% |