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X Demographics
Mendeley readers
Attention Score in Context
| Title |
The role of tau protein in HIV-associated neurocognitive disorders
|
|---|---|
| Published in |
Molecular Neurodegeneration, October 2014
|
| DOI | 10.1186/1750-1326-9-40 |
| Pubmed ID | |
| Authors |
Lecia AM Brown, James Scarola, Adam J Smith, Paul R Sanberg, Jun Tan, Brian Giunta |
| Abstract |
Given the increased life expectancy of human immunodeficiency virus (HIV) infected individuals treated with combination antiretroviral therapy (cART) and the ongoing inflammation observed in the brains of these patients, it is likely that premature neurodegeneration as measured by phospho-tau (p-tau) or increased total tau (t-tau) protein may become an increasing problem. This review examines the seven human studies that have occurred over the past 14 years measuring p-tau and/or t-tau in cerebrospinal fluid (CSF) or via post-mortem brain immunohistochemistry. Although not all studies are in agreement as to the changes in p-and t-tau in HIV infected patients, HIV persists in the brain despite cART. Thus is it is suggested that those maintained on long-term cART may develop tau pathology beyond the extent seen in the studies reviewed herein and overtime may then reach the threshold for clinical manifestation. |
X Demographics
The data shown below were collected from the profiles of 8 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 25% |
| Unknown | 6 | 75% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 8 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 54 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Netherlands | 1 | 2% |
| Unknown | 53 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 11 | 20% |
| Researcher | 6 | 11% |
| Student > Bachelor | 5 | 9% |
| Student > Ph. D. Student | 5 | 9% |
| Student > Postgraduate | 4 | 7% |
| Other | 9 | 17% |
| Unknown | 14 | 26% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 10 | 19% |
| Neuroscience | 10 | 19% |
| Medicine and Dentistry | 10 | 19% |
| Biochemistry, Genetics and Molecular Biology | 4 | 7% |
| Decision Sciences | 2 | 4% |
| Other | 2 | 4% |
| Unknown | 16 | 30% |
Attention Score in Context
This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 September 2023.
All research outputs
#7,256,064
of 25,302,890 outputs
Outputs from Molecular Neurodegeneration
#682
of 968 outputs
Outputs of similar age
#72,413
of 263,002 outputs
Outputs of similar age from Molecular Neurodegeneration
#9
of 14 outputs
Altmetric has tracked 25,302,890 research outputs across all sources so far. This one has received more attention than most of these and is in the 71st percentile.
So far Altmetric has tracked 968 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 16.4. This one is in the 29th percentile – i.e., 29% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 263,002 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 72% of its contemporaries.
We're also able to compare this research output to 14 others from the same source and published within six weeks on either side of this one. This one is in the 42nd percentile – i.e., 42% of its contemporaries scored the same or lower than it.