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Tetramer guided, cell sorter assisted production of clinical grade autologous NY-ESO-1 specific CD8+ T cells

Overview of attention for article published in Journal for Immunotherapy of Cancer, October 2014
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (75th percentile)

Mentioned by

twitter
2 tweeters
patent
1 patent
facebook
1 Facebook page

Citations

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49 Dimensions

Readers on

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85 Mendeley
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Title
Tetramer guided, cell sorter assisted production of clinical grade autologous NY-ESO-1 specific CD8+ T cells
Published in
Journal for Immunotherapy of Cancer, October 2014
DOI 10.1186/s40425-014-0036-y
Pubmed ID
Authors

Seth M Pollack, Robin L Jones, Erik A Farrar, Ivy P Lai, Sylvia M Lee, Jianhong Cao, Venu G Pillarisetty, Benjamin L Hoch, Ashley Gullett, Marie Bleakley, Ernest U Conrad, Janet F Eary, Kendall C Shibuya, Edus H Warren, Jason N Carstens, Shelly Heimfeld, Stanley R Riddell, Cassian Yee

Abstract

Adoptive T cell therapy represents an attractive modality for the treatment of patients with cancer. Peripheral blood mononuclear cells have been used as a source of antigen specific T cells but the very low frequency of T cells recognizing commonly expressed antigens such as NY-ESO-1 limit the applicability of this approach to other solid tumors. To overcome this, we tested a strategy combining IL-21 modulation during in vitro stimulation with first-in-class use of tetramer-guided cell sorting to generate NY-ESO-1 specific cytotoxic T lymphocytes (CTL).

Twitter Demographics

The data shown below were collected from the profiles of 2 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 85 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 1%
Netherlands 1 1%
Germany 1 1%
Unknown 82 96%

Demographic breakdown

Readers by professional status Count As %
Researcher 20 24%
Student > Ph. D. Student 13 15%
Student > Master 10 12%
Other 9 11%
Student > Bachelor 6 7%
Other 12 14%
Unknown 15 18%
Readers by discipline Count As %
Agricultural and Biological Sciences 16 19%
Immunology and Microbiology 15 18%
Medicine and Dentistry 15 18%
Biochemistry, Genetics and Molecular Biology 10 12%
Engineering 5 6%
Other 6 7%
Unknown 18 21%

Attention Score in Context

This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 May 2021.
All research outputs
#5,560,469
of 21,200,018 outputs
Outputs from Journal for Immunotherapy of Cancer
#1,174
of 2,547 outputs
Outputs of similar age
#55,796
of 227,300 outputs
Outputs of similar age from Journal for Immunotherapy of Cancer
#1
of 2 outputs
Altmetric has tracked 21,200,018 research outputs across all sources so far. This one has received more attention than most of these and is in the 73rd percentile.
So far Altmetric has tracked 2,547 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 14.1. This one has gotten more attention than average, scoring higher than 53% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 227,300 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 75% of its contemporaries.
We're also able to compare this research output to 2 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them