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Tetramer guided, cell sorter assisted production of clinical grade autologous NY-ESO-1 specific CD8+ T cells

Overview of attention for article published in Journal for Immunotherapy of Cancer, October 2014
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (86th percentile)
  • High Attention Score compared to outputs of the same age and source (92nd percentile)

Mentioned by

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2 X users
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4 patents
facebook
1 Facebook page

Citations

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57 Dimensions

Readers on

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90 Mendeley
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Title
Tetramer guided, cell sorter assisted production of clinical grade autologous NY-ESO-1 specific CD8+ T cells
Published in
Journal for Immunotherapy of Cancer, October 2014
DOI 10.1186/s40425-014-0036-y
Pubmed ID
Authors

Seth M Pollack, Robin L Jones, Erik A Farrar, Ivy P Lai, Sylvia M Lee, Jianhong Cao, Venu G Pillarisetty, Benjamin L Hoch, Ashley Gullett, Marie Bleakley, Ernest U Conrad, Janet F Eary, Kendall C Shibuya, Edus H Warren, Jason N Carstens, Shelly Heimfeld, Stanley R Riddell, Cassian Yee

Abstract

Adoptive T cell therapy represents an attractive modality for the treatment of patients with cancer. Peripheral blood mononuclear cells have been used as a source of antigen specific T cells but the very low frequency of T cells recognizing commonly expressed antigens such as NY-ESO-1 limit the applicability of this approach to other solid tumors. To overcome this, we tested a strategy combining IL-21 modulation during in vitro stimulation with first-in-class use of tetramer-guided cell sorting to generate NY-ESO-1 specific cytotoxic T lymphocytes (CTL).

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 90 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 1%
Netherlands 1 1%
Germany 1 1%
Unknown 87 97%

Demographic breakdown

Readers by professional status Count As %
Researcher 21 23%
Student > Ph. D. Student 13 14%
Other 10 11%
Student > Master 10 11%
Student > Bachelor 8 9%
Other 12 13%
Unknown 16 18%
Readers by discipline Count As %
Agricultural and Biological Sciences 17 19%
Medicine and Dentistry 16 18%
Immunology and Microbiology 16 18%
Biochemistry, Genetics and Molecular Biology 11 12%
Engineering 5 6%
Other 6 7%
Unknown 19 21%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 11. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 October 2023.
All research outputs
#3,236,874
of 25,461,852 outputs
Outputs from Journal for Immunotherapy of Cancer
#880
of 3,436 outputs
Outputs of similar age
#35,458
of 268,305 outputs
Outputs of similar age from Journal for Immunotherapy of Cancer
#5
of 67 outputs
Altmetric has tracked 25,461,852 research outputs across all sources so far. Compared to these this one has done well and is in the 87th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,436 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.7. This one has gotten more attention than average, scoring higher than 74% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 268,305 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 86% of its contemporaries.
We're also able to compare this research output to 67 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 92% of its contemporaries.