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Effect of Ebola virus proteins GP, NP and VP35 on VP40 VLP morphology

Overview of attention for article published in Virology Journal, May 2006
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Title
Effect of Ebola virus proteins GP, NP and VP35 on VP40 VLP morphology
Published in
Virology Journal, May 2006
DOI 10.1186/1743-422x-3-31
Pubmed ID
Authors

Reed F Johnson, Peter Bell, Ronald N Harty

Abstract

Recently we described a role for Ebola virus proteins, NP, GP, and VP35 in enhancement of VP40 VLP budding. To explore the possibility that VLP structure was altered by co-expression of EBOV proteins leading to the observed enhancement of VP40 VLP budding, we performed density gradient analysis as well as electron microscopy studies. Our data suggest that VP40 is the major determinant of VLP morphology, as co-expression of NP, GP and VP35 did not significantly change VLP density, length, and diameter. Ultra-structural changes were noted in the core of the VLPs when NP was co-expressed with VP40. Overall, these findings indicate that major changes in morphology of VP40 VLPs were likely not responsible for enhanced budding of VP40 VLPs in the presence of GP, NP and/or VP35.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 105 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 2%
Vietnam 1 <1%
United Kingdom 1 <1%
Lithuania 1 <1%
Russia 1 <1%
Canada 1 <1%
Unknown 98 93%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 21 20%
Student > Bachelor 16 15%
Researcher 15 14%
Student > Master 10 10%
Other 5 5%
Other 16 15%
Unknown 22 21%
Readers by discipline Count As %
Agricultural and Biological Sciences 26 25%
Immunology and Microbiology 13 12%
Biochemistry, Genetics and Molecular Biology 12 11%
Medicine and Dentistry 10 10%
Chemistry 5 5%
Other 17 16%
Unknown 22 21%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 October 2014.
All research outputs
#20,239,689
of 22,766,595 outputs
Outputs from Virology Journal
#2,874
of 3,040 outputs
Outputs of similar age
#63,459
of 65,603 outputs
Outputs of similar age from Virology Journal
#6
of 6 outputs
Altmetric has tracked 22,766,595 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,040 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 25.7. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 65,603 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 6 others from the same source and published within six weeks on either side of this one.