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Mitochondrial structure alteration in human prostate cancer cells upon initial interaction with a chemopreventive agent phenethyl isothiocyanate

Overview of attention for article published in Cancer Cell International, March 2014
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • One of the highest-scoring outputs from this source (#3 of 1,793)
  • High Attention Score compared to outputs of the same age (97th percentile)
  • High Attention Score compared to outputs of the same age and source (91st percentile)

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1 X user
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532 Facebook pages

Citations

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17 Dimensions

Readers on

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15 Mendeley
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Title
Mitochondrial structure alteration in human prostate cancer cells upon initial interaction with a chemopreventive agent phenethyl isothiocyanate
Published in
Cancer Cell International, March 2014
DOI 10.1186/1475-2867-14-30
Pubmed ID
Authors

Chengsen Xue, Hilda A Pasolli, Irene Piscopo, Daniel J Gros, Christina Liu, Yamei Chen, Jen Wei Chiao

Abstract

Phenethyl isothiocyanate (PEITC), present naturally in cruciferous vegetables, is a chemopreventive agent. It blocks initiation and post-initiation progression of carcinogenesis. Mechanism study in human prostate cancer cells revealed that PEITC is a dual inhibitor of aberrant DNA hypermethylation and histone deacetylases, reactivating silenced genes and regulating the androgen-mediated growth of tumor cells. The identity of the cellular organelle that initially interacts with PEITC has not been fully described.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 15 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 15 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 3 20%
Student > Ph. D. Student 3 20%
Student > Bachelor 2 13%
Professor > Associate Professor 2 13%
Student > Master 2 13%
Other 2 13%
Unknown 1 7%
Readers by discipline Count As %
Agricultural and Biological Sciences 5 33%
Medicine and Dentistry 3 20%
Biochemistry, Genetics and Molecular Biology 2 13%
Nursing and Health Professions 1 7%
Chemistry 1 7%
Other 0 0%
Unknown 3 20%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 69. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 June 2015.
All research outputs
#523,251
of 22,766,595 outputs
Outputs from Cancer Cell International
#3
of 1,793 outputs
Outputs of similar age
#5,199
of 226,196 outputs
Outputs of similar age from Cancer Cell International
#1
of 12 outputs
Altmetric has tracked 22,766,595 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 97th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,793 research outputs from this source. They receive a mean Attention Score of 3.8. This one has done particularly well, scoring higher than 99% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 226,196 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 97% of its contemporaries.
We're also able to compare this research output to 12 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 91% of its contemporaries.