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SPARC mediates metastatic cooperation between CSC and non-CSC prostate cancer cell subpopulations

Overview of attention for article published in Molecular Cancer, October 2014
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (71st percentile)
  • Good Attention Score compared to outputs of the same age and source (76th percentile)

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8 X users
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1 Facebook page

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87 Mendeley
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Title
SPARC mediates metastatic cooperation between CSC and non-CSC prostate cancer cell subpopulations
Published in
Molecular Cancer, October 2014
DOI 10.1186/1476-4598-13-237
Pubmed ID
Authors

Francesca Mateo, Óscar Meca-Cortés, Toni Celià-Terrassa, Yolanda Fernández, Ibane Abasolo, Lourdes Sánchez-Cid, Raquel Bermudo, Amaia Sagasta, Leonardo Rodríguez-Carunchio, Mònica Pons, Verónica Cánovas, Mercedes Marín-Aguilera, Lourdes Mengual, Antonio Alcaraz, Simó Schwartz, Begoña Mellado, Kristina Y Aguilera, Rolf Brekken, Pedro L Fernández, Rosanna Paciucci, Timothy M Thomson

Abstract

Tumor cell subpopulations can either compete with each other for nutrients and physical space within the tumor niche, or co-operate for enhanced survival, or replicative or metastatic capacities. Recently, we have described co-operative interactions between two clonal subpopulations derived from the PC-3 prostate cancer cell line, in which the invasiveness of a cancer stem cell (CSC)-enriched subpopulation (PC-3M, or M) is enhanced by a non-CSC subpopulation (PC-3S, or S), resulting in their accelerated metastatic dissemination.

X Demographics

X Demographics

The data shown below were collected from the profiles of 8 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 87 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 1%
Germany 1 1%
Unknown 85 98%

Demographic breakdown

Readers by professional status Count As %
Researcher 21 24%
Student > Ph. D. Student 16 18%
Student > Bachelor 14 16%
Other 7 8%
Student > Master 7 8%
Other 12 14%
Unknown 10 11%
Readers by discipline Count As %
Agricultural and Biological Sciences 25 29%
Biochemistry, Genetics and Molecular Biology 21 24%
Medicine and Dentistry 15 17%
Engineering 2 2%
Immunology and Microbiology 1 1%
Other 9 10%
Unknown 14 16%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 July 2016.
All research outputs
#6,407,957
of 22,768,097 outputs
Outputs from Molecular Cancer
#447
of 1,719 outputs
Outputs of similar age
#70,639
of 259,774 outputs
Outputs of similar age from Molecular Cancer
#9
of 38 outputs
Altmetric has tracked 22,768,097 research outputs across all sources so far. This one has received more attention than most of these and is in the 70th percentile.
So far Altmetric has tracked 1,719 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.7. This one has gotten more attention than average, scoring higher than 72% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 259,774 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 71% of its contemporaries.
We're also able to compare this research output to 38 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 76% of its contemporaries.