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Glucose restriction decreases telomerase activity and enhances its inhibitor response on breast cancer cells: possible extra-telomerase role of BIBR 1532

Overview of attention for article published in Cancer Cell International, July 2014
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (80th percentile)
  • High Attention Score compared to outputs of the same age and source (80th percentile)

Mentioned by

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8 X users
facebook
1 Facebook page

Citations

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26 Dimensions

Readers on

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40 Mendeley
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Title
Glucose restriction decreases telomerase activity and enhances its inhibitor response on breast cancer cells: possible extra-telomerase role of BIBR 1532
Published in
Cancer Cell International, July 2014
DOI 10.1186/1475-2867-14-60
Pubmed ID
Authors

Layal Wardi, Nada Alaaeddine, Issam Raad, Riad Sarkis, Rim Serhal, Charbel Khalil, George Hilal

Abstract

Considerable progress has been made to understand the association between lifestyle and diet in cancer initiation and promotion. Because excessive glucose consumption is a key metabolic hallmark of cancer cells, glucose restriction (GR) decreases the proliferation, and promotes the differentiation and transformation of cancer cells to quiescent cells. The immortality of cancerous cells is largely assured by telomerase, which is an interesting target for inhibition by BIBR 1532. In this study, we investigated the effect of GR on telomerase activity and on the efficacy of its inhibition by BIBR 1532.

X Demographics

X Demographics

The data shown below were collected from the profiles of 8 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 40 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 3%
India 1 3%
Brazil 1 3%
Unknown 37 93%

Demographic breakdown

Readers by professional status Count As %
Student > Master 7 18%
Student > Ph. D. Student 6 15%
Student > Bachelor 4 10%
Researcher 4 10%
Other 2 5%
Other 6 15%
Unknown 11 28%
Readers by discipline Count As %
Agricultural and Biological Sciences 10 25%
Medicine and Dentistry 7 18%
Biochemistry, Genetics and Molecular Biology 5 13%
Nursing and Health Professions 1 3%
Environmental Science 1 3%
Other 2 5%
Unknown 14 35%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 7. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 October 2019.
All research outputs
#4,468,500
of 22,768,097 outputs
Outputs from Cancer Cell International
#458
of 1,793 outputs
Outputs of similar age
#44,161
of 227,406 outputs
Outputs of similar age from Cancer Cell International
#2
of 10 outputs
Altmetric has tracked 22,768,097 research outputs across all sources so far. Compared to these this one has done well and is in the 80th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,793 research outputs from this source. They receive a mean Attention Score of 3.8. This one has gotten more attention than average, scoring higher than 74% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 227,406 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 80% of its contemporaries.
We're also able to compare this research output to 10 others from the same source and published within six weeks on either side of this one. This one has scored higher than 8 of them.