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Gene expression patterns and sequence polymorphisms associated with mosquito resistance to Bacillus thuringiensis israelensis toxins

Overview of attention for article published in BMC Genomics, October 2014
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  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (92nd percentile)
  • High Attention Score compared to outputs of the same age and source (95th percentile)

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Title
Gene expression patterns and sequence polymorphisms associated with mosquito resistance to Bacillus thuringiensis israelensis toxins
Published in
BMC Genomics, October 2014
DOI 10.1186/1471-2164-15-926
Pubmed ID
Authors

Laurence Després, Renaud Stalinski, Guillaume Tetreau, Margot Paris, Aurélie Bonin, Vincent Navratil, Stéphane Reynaud, Jean-Philippe David

Abstract

Despite the intensive use of Bacillus thuringiensis israelensis (Bti) toxins for mosquito control, little is known about the long term effect of exposure to this cocktail of toxins on target mosquito populations. In contrast to the many cases of resistance to Bacillus thuringiensis Cry toxins observed in other insects, there is no evidence so far for Bti resistance evolution in field mosquito populations. High fitness costs measured in a Bti selected mosquito laboratory strain suggest that evolving resistance to Bti is costly. The aim of the present study was to identify transcription level and polymorphism variations associated with resistance to Bti toxins in the dengue vector Aedes aegypti. We used RNA sequencing (RNA-seq) for comparing a laboratory-selected strain showing elevated resistance to Bti toxins and its parental non-selected susceptible strain. As the resistant strain displayed two marked larval development phenotypes (slow and normal), each phenotype was analyzed separately in order to evidence potential links between resistance mechanisms and mosquito life-history traits.

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The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 83 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Portugal 1 1%
Germany 1 1%
France 1 1%
United Kingdom 1 1%
United States 1 1%
Unknown 78 94%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 16 19%
Student > Master 11 13%
Student > Bachelor 11 13%
Student > Doctoral Student 9 11%
Researcher 9 11%
Other 12 14%
Unknown 15 18%
Readers by discipline Count As %
Agricultural and Biological Sciences 37 45%
Biochemistry, Genetics and Molecular Biology 14 17%
Medicine and Dentistry 5 6%
Environmental Science 3 4%
Immunology and Microbiology 3 4%
Other 5 6%
Unknown 16 19%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 21. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 02 August 2016.
All research outputs
#1,775,835
of 25,371,288 outputs
Outputs from BMC Genomics
#366
of 11,244 outputs
Outputs of similar age
#20,099
of 273,324 outputs
Outputs of similar age from BMC Genomics
#12
of 302 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 92nd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 11,244 research outputs from this source. They receive a mean Attention Score of 4.8. This one has done particularly well, scoring higher than 96% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 273,324 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 92% of its contemporaries.
We're also able to compare this research output to 302 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 95% of its contemporaries.