Title |
Variation in exposure to Anopheles gambiae salivary gland peptide (gSG6-P1) across different malaria transmission settings in the western Kenya highlands
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Published in |
Malaria Journal, September 2012
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DOI | 10.1186/1475-2875-11-318 |
Pubmed ID | |
Authors |
Kingsley Badu, Joram Siangla, John Larbi, Bernard W Lawson, Yaw Afrane, John Ong’echa, Franck Remoue, Guofa Zhou, Andrew K Githeko, Guiyun Yan |
Abstract |
The existing metrics of malaria transmission are limited in sensitivity under low transmission intensity. Robust surveillance systems are needed as interventions to monitor reduced transmission and prevention of rapid reintroduction. Serological tools based on antibody responses to parasite and vector antigens are potential tools for transmission measurements. The current study sought to evaluate antibody responses to Anopheles gambiae salivary gland peptide (gSG6- P1), as a biomarker of human exposure to Anopheles bites, in different transmission settings and seasons. The comparison between anti-MSP-1(19) IgG immune responders and non-responders allowed exploring the robustness of the gSG6-P1 peptide as a surveillance tool in an area of decreasing malaria transmission. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 1 | 1% |
France | 1 | 1% |
Ghana | 1 | 1% |
Unknown | 65 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 10 | 15% |
Researcher | 9 | 13% |
Student > Bachelor | 7 | 10% |
Student > Ph. D. Student | 7 | 10% |
Student > Doctoral Student | 5 | 7% |
Other | 16 | 24% |
Unknown | 14 | 21% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 20 | 29% |
Medicine and Dentistry | 11 | 16% |
Biochemistry, Genetics and Molecular Biology | 9 | 13% |
Immunology and Microbiology | 6 | 9% |
Computer Science | 2 | 3% |
Other | 7 | 10% |
Unknown | 13 | 19% |