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Attention Score in Context
| Title |
RpoS integrates CRP, Fis, and PhoP signaling pathways to control Salmonella Typhi hlyE expression
|
|---|---|
| Published in |
BMC Microbiology, May 2014
|
| DOI | 10.1186/1471-2180-14-139 |
| Pubmed ID | |
| Authors |
Matías R Jofré, Leonardo M Rodríguez, Nicolás A Villagra, Alejandro A Hidalgo, Guido C Mora, Juan A Fuentes |
| Abstract |
SPI-18 is a pathogenicity island found in some Salmonella enterica serovars, including S. Typhi. SPI-18 harbors two ORFs organized into an operon, hlyE and taiA genes, both implicated in virulence. Regarding the hlyE regulation in S. Typhi, it has been reported that RpoS participates as transcriptional up-regulator under low pH and high osmolarity. In addition, CRP down-regulates hlyE expression during exponential growth. Previously, it has been suggested that there is another factor related to catabolite repression, different from CRP, involved in the down-regulation of hlyE. Moreover, PhoP-dependent hlyE up-regulation has been reported in bacteria cultured simultaneously under low pH and low concentration of Mg2+. Nevertheless, the relative contribution of each environmental signal is not completely clear. In this work we aimed to better understand the regulation of hlyE in S. Typhi and the integration of different environmental signals through global regulators. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 40 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Chile | 3 | 8% |
| Unknown | 37 | 93% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 11 | 28% |
| Student > Master | 7 | 18% |
| Researcher | 6 | 15% |
| Student > Bachelor | 4 | 10% |
| Student > Doctoral Student | 1 | 3% |
| Other | 4 | 10% |
| Unknown | 7 | 18% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 17 | 43% |
| Biochemistry, Genetics and Molecular Biology | 10 | 25% |
| Immunology and Microbiology | 4 | 10% |
| Chemistry | 1 | 3% |
| Unknown | 8 | 20% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 October 2014.
All research outputs
#20,241,019
of 22,768,097 outputs
Outputs from BMC Microbiology
#2,685
of 3,184 outputs
Outputs of similar age
#192,272
of 226,984 outputs
Outputs of similar age from BMC Microbiology
#43
of 51 outputs
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So far Altmetric has tracked 3,184 research outputs from this source. They receive a mean Attention Score of 4.1. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
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We're also able to compare this research output to 51 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.