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Added predictive value of omics data: specific issues related to validation illustrated by two case studies

Overview of attention for article published in BMC Medical Research Methodology, October 2014
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Title
Added predictive value of omics data: specific issues related to validation illustrated by two case studies
Published in
BMC Medical Research Methodology, October 2014
DOI 10.1186/1471-2288-14-117
Pubmed ID
Authors

Riccardo De Bin, Tobias Herold, Anne-Laure Boulesteix

Abstract

In the last years, the importance of independent validation of the prediction ability of a new gene signature has been largely recognized. Recently, with the development of gene signatures which integrate rather than replace the clinical predictors in the prediction rule, the focus has been moved to the validation of the added predictive value of a gene signature, i.e. to the verification that the inclusion of the new gene signature in a prediction model is able to improve its prediction ability.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 27 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 4%
Netherlands 1 4%
France 1 4%
Germany 1 4%
Unknown 23 85%

Demographic breakdown

Readers by professional status Count As %
Researcher 10 37%
Student > Bachelor 3 11%
Student > Ph. D. Student 3 11%
Student > Master 2 7%
Student > Doctoral Student 1 4%
Other 4 15%
Unknown 4 15%
Readers by discipline Count As %
Medicine and Dentistry 6 22%
Computer Science 5 19%
Agricultural and Biological Sciences 4 15%
Biochemistry, Genetics and Molecular Biology 4 15%
Mathematics 3 11%
Other 1 4%
Unknown 4 15%