Title |
A group LASSO-based method for robustly inferring gene regulatory networks from multiple time-course datasets
|
---|---|
Published in |
BMC Systems Biology, October 2014
|
DOI | 10.1186/1752-0509-8-s3-s1 |
Pubmed ID | |
Authors |
Li-Zhi Liu, Fang-Xiang Wu, Wen-Jun Zhang |
Abstract |
As an abstract mapping of the gene regulations in the cell, gene regulatory network is important to both biological research study and practical applications. The reverse engineering of gene regulatory networks from microarray gene expression data is a challenging research problem in systems biology. With the development of biological technologies, multiple time-course gene expression datasets might be collected for a specific gene network under different circumstances. The inference of a gene regulatory network can be improved by integrating these multiple datasets. It is also known that gene expression data may be contaminated with large errors or outliers, which may affect the inference results. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
France | 1 | 50% |
United States | 1 | 50% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Netherlands | 1 | 3% |
Germany | 1 | 3% |
Unknown | 29 | 94% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 12 | 39% |
Student > Ph. D. Student | 9 | 29% |
Professor | 2 | 6% |
Student > Master | 2 | 6% |
Lecturer | 1 | 3% |
Other | 2 | 6% |
Unknown | 3 | 10% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 7 | 23% |
Biochemistry, Genetics and Molecular Biology | 6 | 19% |
Computer Science | 6 | 19% |
Mathematics | 2 | 6% |
Social Sciences | 2 | 6% |
Other | 4 | 13% |
Unknown | 4 | 13% |