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The triggering receptor expressed on myeloid cells (TREM) in inflammatory bowel disease pathogenesis

Overview of attention for article published in Journal of Translational Medicine, October 2014
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (81st percentile)
  • High Attention Score compared to outputs of the same age and source (80th percentile)

Mentioned by

twitter
2 X users
patent
1 patent
wikipedia
1 Wikipedia page

Citations

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39 Dimensions

Readers on

mendeley
99 Mendeley
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Title
The triggering receptor expressed on myeloid cells (TREM) in inflammatory bowel disease pathogenesis
Published in
Journal of Translational Medicine, October 2014
DOI 10.1186/s12967-014-0293-z
Pubmed ID
Authors

Marco Genua, Sergio Rutella, Carmen Correale, Silvio Danese

Abstract

The Triggering Receptors Expressed on Myeloid cells (TREM) are a family of cell-surface molecules that control inflammation, bone homeostasis, neurological development and blood coagulation. TREM-1 and TREM-2, the best-characterized receptors so far, play divergent roles in several infectious diseases. In the intestine, TREM-1 is highly expressed by macrophages, contributing to inflammatory bowel disease (IBD) pathogenesis. Contrary to current understanding, TREM-2 also promotes inflammation in IBD by fueling dendritic cell functions. This review will focus specifically on recent insights into the role of TREM proteins in IBD development, and discuss opportunities for novel treatment approaches.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 99 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Brazil 2 2%
Unknown 97 98%

Demographic breakdown

Readers by professional status Count As %
Researcher 21 21%
Student > Master 13 13%
Student > Ph. D. Student 12 12%
Student > Bachelor 9 9%
Student > Postgraduate 7 7%
Other 16 16%
Unknown 21 21%
Readers by discipline Count As %
Agricultural and Biological Sciences 19 19%
Biochemistry, Genetics and Molecular Biology 18 18%
Medicine and Dentistry 17 17%
Immunology and Microbiology 5 5%
Pharmacology, Toxicology and Pharmaceutical Science 5 5%
Other 15 15%
Unknown 20 20%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 8. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 December 2021.
All research outputs
#4,077,245
of 22,663,969 outputs
Outputs from Journal of Translational Medicine
#651
of 3,954 outputs
Outputs of similar age
#47,588
of 260,291 outputs
Outputs of similar age from Journal of Translational Medicine
#18
of 93 outputs
Altmetric has tracked 22,663,969 research outputs across all sources so far. Compared to these this one has done well and is in the 81st percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,954 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.5. This one has done well, scoring higher than 83% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 260,291 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 81% of its contemporaries.
We're also able to compare this research output to 93 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 80% of its contemporaries.