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Up-regulation on cytochromes P450 in rat mediated by total alkaloid extract from Corydalis yanhusuo

Overview of attention for article published in BMC Complementary Medicine and Therapies, August 2014
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Title
Up-regulation on cytochromes P450 in rat mediated by total alkaloid extract from Corydalis yanhusuo
Published in
BMC Complementary Medicine and Therapies, August 2014
DOI 10.1186/1472-6882-14-306
Pubmed ID
Authors

Jingjing Yan, Xin He, Shan Feng, Yiran Zhai, Yetao Ma, Sheng Liang, Chunhuan Jin

Abstract

Yanhusuo (Corydalis yanhusuo W.T. Wang; YHS), is a well-known traditional Chinese herbal medicine, has been used in China for treating pain including chest pain, epigastric pain, and dysmenorrhea. Its alkaloid ingredients including tetrahydropalmatine are reported to inhibit cytochromes P450 (CYPs) activity in vitro. The present study is aimed to assess the potential of total alkaloid extract (TAE) from YHS to effect the activity and mRNA levels of five cytochromes P450 (CYPs) in rat.

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X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 16 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
India 1 6%
Unknown 15 94%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 2 13%
Researcher 2 13%
Student > Postgraduate 2 13%
Student > Master 2 13%
Lecturer 1 6%
Other 3 19%
Unknown 4 25%
Readers by discipline Count As %
Medicine and Dentistry 3 19%
Pharmacology, Toxicology and Pharmaceutical Science 2 13%
Nursing and Health Professions 2 13%
Immunology and Microbiology 1 6%
Agricultural and Biological Sciences 1 6%
Other 2 13%
Unknown 5 31%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 October 2014.
All research outputs
#20,242,136
of 22,769,322 outputs
Outputs from BMC Complementary Medicine and Therapies
#2,971
of 3,623 outputs
Outputs of similar age
#197,145
of 235,042 outputs
Outputs of similar age from BMC Complementary Medicine and Therapies
#95
of 111 outputs
Altmetric has tracked 22,769,322 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,623 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.5. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 235,042 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 111 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.