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X Demographics
Mendeley readers
Attention Score in Context
| Title |
PLD3 is accumulated on neuritic plaques in Alzheimer’s disease brains
|
|---|---|
| Published in |
Alzheimer's Research & Therapy, November 2014
|
| DOI | 10.1186/s13195-014-0070-5 |
| Pubmed ID | |
| Authors |
Jun-ichi Satoh, Yoshihiro Kino, Yoji Yamamoto, Natsuki Kawana, Tsuyoshi Ishida, Yuko Saito, Kunimasa Arima |
| Abstract |
Recently, a whole-exome sequencing (WES) study showed that a rare variant rs145999145 composed of p.Val232Met located in exon 7 of the phospholipase D3 (PLD3) gene confers a doubled risk for late-onset Alzheimer's disease (AD). Knockdown of PLD3 elevates the levels of extracellular amyloid-beta (Aβ), suggesting that PLD3 acts as a negative regulator of Aβ precursor protein (APP) processing. However, the precise cellular location and distribution of PLD3 in AD brains remain largely unknown. |
X Demographics
The data shown below were collected from the profiles of 6 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 17% |
| United States | 1 | 17% |
| Unknown | 4 | 67% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3 | 50% |
| Practitioners (doctors, other healthcare professionals) | 1 | 17% |
| Science communicators (journalists, bloggers, editors) | 1 | 17% |
| Scientists | 1 | 17% |
Mendeley readers
The data shown below were compiled from readership statistics for 88 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 1% |
| Korea, Republic of | 1 | 1% |
| Luxembourg | 1 | 1% |
| Unknown | 85 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 19 | 22% |
| Student > Ph. D. Student | 16 | 18% |
| Student > Master | 8 | 9% |
| Student > Doctoral Student | 7 | 8% |
| Student > Bachelor | 4 | 5% |
| Other | 12 | 14% |
| Unknown | 22 | 25% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 16 | 18% |
| Neuroscience | 14 | 16% |
| Biochemistry, Genetics and Molecular Biology | 9 | 10% |
| Medicine and Dentistry | 9 | 10% |
| Pharmacology, Toxicology and Pharmaceutical Science | 4 | 5% |
| Other | 13 | 15% |
| Unknown | 23 | 26% |
Attention Score in Context
This research output has an Altmetric Attention Score of 15. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 30 November 2017.
All research outputs
#1,995,976
of 22,769,322 outputs
Outputs from Alzheimer's Research & Therapy
#415
of 1,211 outputs
Outputs of similar age
#24,941
of 261,400 outputs
Outputs of similar age from Alzheimer's Research & Therapy
#6
of 13 outputs
Altmetric has tracked 22,769,322 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 91st percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,211 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 24.2. This one has gotten more attention than average, scoring higher than 65% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 261,400 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 90% of its contemporaries.
We're also able to compare this research output to 13 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 53% of its contemporaries.