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Renal clear cell carcinoma metastasis to the breast ten years after nephrectomy: a case report and literature review

Overview of attention for article published in Diagnostic Pathology, November 2017
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Title
Renal clear cell carcinoma metastasis to the breast ten years after nephrectomy: a case report and literature review
Published in
Diagnostic Pathology, November 2017
DOI 10.1186/s13000-017-0666-8
Pubmed ID
Authors

Yanjun Xu, Rui Hou, Qijie Lu, Yifan Deng, Bin Hu

Abstract

Renal cell carcinoma most commonly metastasizes to the lungs, skeleton or liver. Metastatic renal cell carcinoma to the breast is very rare, especially for clear cell carcinoma, and few cases regarding this condition have been reported. The case we presented was a 68-year-old Chinese female with metastatic renal clear cell carcinoma of the left breast 10 years after a nephrectomy. Identification of the metastatic renal clear cell carcinoma in the breast required multiple breast imaging modalities. Imaging showed a single, ovary-shaped, well-defined hypo-echoic mass, with abundant blood flow on ultrasound images. The mass was enhanced early on MRI, and it was hypointense on a T1-weighted image and hyperintense on a fat-saturated T2-weighted image. Following surgical excision of the tumor, a routine immunohistochemistry antibody panel on the tumor cells revealed negative staining for estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor-2 (Her-2). Strong positive staining for the cluster of differentiation 10 (CD10) and vimentin was present. This case is unusual because of the site of metastatic progression. It is important for physicians to be aware of this progression so early diagnoses can be made, and appropriate therapeutic planning can be initiated.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 15 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 15 100%

Demographic breakdown

Readers by professional status Count As %
Student > Postgraduate 3 20%
Other 2 13%
Student > Master 2 13%
Student > Ph. D. Student 1 7%
Lecturer 1 7%
Other 2 13%
Unknown 4 27%
Readers by discipline Count As %
Medicine and Dentistry 10 67%
Materials Science 1 7%
Computer Science 1 7%
Unknown 3 20%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 November 2017.
All research outputs
#18,575,277
of 23,007,053 outputs
Outputs from Diagnostic Pathology
#762
of 1,135 outputs
Outputs of similar age
#252,154
of 329,244 outputs
Outputs of similar age from Diagnostic Pathology
#10
of 16 outputs
Altmetric has tracked 23,007,053 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,135 research outputs from this source. They receive a mean Attention Score of 2.8. This one is in the 16th percentile – i.e., 16% of its peers scored the same or lower than it.
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We're also able to compare this research output to 16 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.