Title |
Gene-nutrient interactions and susceptibility to human obesity
|
---|---|
Published in |
Genes & Nutrition, October 2017
|
DOI | 10.1186/s12263-017-0581-3 |
Pubmed ID | |
Authors |
Joseph J. Castillo, Robert A. Orlando, William S. Garver |
Abstract |
A large number of genome-wide association studies, transferability studies, and candidate gene studies performed in diverse populations around the world have identified gene variants that are associated with common human obesity. The mounting evidence suggests that these obesity gene variants interact with multiple environmental factors and increase susceptibility to this complex metabolic disease. The objective of this review article is to provide concise and updated information on energy balance, heritability of body weight, origins of gene variants, and gene-nutrient interactions in relation to human obesity. It is proposed that knowledge of these related topics will provide valuable insight for future preventative lifestyle intervention using targeted nutritional and medicinal therapies. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 1 | 14% |
United States | 1 | 14% |
Italy | 1 | 14% |
Switzerland | 1 | 14% |
Unknown | 3 | 43% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 4 | 57% |
Practitioners (doctors, other healthcare professionals) | 2 | 29% |
Scientists | 1 | 14% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 98 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 15 | 15% |
Student > Master | 14 | 14% |
Student > Bachelor | 11 | 11% |
Researcher | 5 | 5% |
Student > Doctoral Student | 4 | 4% |
Other | 16 | 16% |
Unknown | 33 | 34% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 17 | 17% |
Medicine and Dentistry | 10 | 10% |
Nursing and Health Professions | 6 | 6% |
Agricultural and Biological Sciences | 5 | 5% |
Pharmacology, Toxicology and Pharmaceutical Science | 5 | 5% |
Other | 16 | 16% |
Unknown | 39 | 40% |