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Attention Score in Context
| Title |
Strategies for gene disruption in Drosophila
|
|---|---|
| Published in |
Cell & Bioscience, October 2014
|
| DOI | 10.1186/2045-3701-4-63 |
| Pubmed ID | |
| Authors |
Shih-Ching Lin, Yu-Yun Chang, Chih-Chiang Chan |
| Abstract |
Drosophila melanogaster has been a classic model organism for the studies of genetics. More than 15,000 Drosophila genes have been annotated since the entire genome was sequenced; however, many of them still lack functional characterization. Various gene-manipulating approaches in Drosophila have been developed for the function analysis of genes. Here, we summarize some representative strategies utilized for Drosophila gene targeting, from the unbiased ethyl methanesulfonate (EMS) mutagenesis and transposable element insertion, to insertional/replacement homologous recombination and site-specific nucleases such as the zinc-finger nuclease (ZFN), the transcription activator-like effector nuclease (TALEN) and the CRISPR (clustered regularly interspaced short palindromic repeats)/Cas9 system. Specifically, we evaluate the pros and cons of each technique in a historical perspective. This review discuss important factors that should be taken into consideration for the selection of a strategy that best fits the specific needs of a gene knockout project. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Australia | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 144 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Spain | 2 | 1% |
| United States | 2 | 1% |
| Japan | 1 | <1% |
| China | 1 | <1% |
| Unknown | 138 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 31 | 22% |
| Student > Bachelor | 31 | 22% |
| Student > Master | 18 | 13% |
| Researcher | 17 | 12% |
| Student > Doctoral Student | 8 | 6% |
| Other | 14 | 10% |
| Unknown | 25 | 17% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 63 | 44% |
| Biochemistry, Genetics and Molecular Biology | 32 | 22% |
| Neuroscience | 12 | 8% |
| Medicine and Dentistry | 5 | 3% |
| Immunology and Microbiology | 2 | 1% |
| Other | 4 | 3% |
| Unknown | 26 | 18% |
Attention Score in Context
This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 November 2023.
All research outputs
#7,229,289
of 23,577,654 outputs
Outputs from Cell & Bioscience
#160
of 1,002 outputs
Outputs of similar age
#76,675
of 257,435 outputs
Outputs of similar age from Cell & Bioscience
#2
of 7 outputs
Altmetric has tracked 23,577,654 research outputs across all sources so far. This one has received more attention than most of these and is in the 68th percentile.
So far Altmetric has tracked 1,002 research outputs from this source. They receive a mean Attention Score of 3.7. This one has done well, scoring higher than 82% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 257,435 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 69% of its contemporaries.
We're also able to compare this research output to 7 others from the same source and published within six weeks on either side of this one. This one has scored higher than 5 of them.