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A nucleosomal approach to inferring causal relationships of histone modifications

Overview of attention for article published in BMC Genomics, January 2014
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Title
A nucleosomal approach to inferring causal relationships of histone modifications
Published in
BMC Genomics, January 2014
DOI 10.1186/1471-2164-15-s1-s7
Pubmed ID
Authors

Ngoc Tu Le, Tu Bao Ho, Bich Hai Ho, Dang Hung Tran

Abstract

Histone proteins are subject to various posttranslational modifications (PTMs). Elucidating their functional relationships is crucial toward understanding many biological processes. Bayesian network (BN)-based approaches have shown the advantage of revealing causal relationships, rather than simple cooccurrences, of PTMs. Previous works employing BNs to infer causal relationships of PTMs require that all confounders should be included. This assumption, however, is unavoidably violated given the fact that several modifications are often regulated by a common but unobserved factor. An existing non-parametric method can be applied to tackle the problem but the complexity and inflexibility make it impractical.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 15 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 7%
Unknown 14 93%

Demographic breakdown

Readers by professional status Count As %
Researcher 8 53%
Student > Ph. D. Student 3 20%
Professor > Associate Professor 2 13%
Student > Bachelor 1 7%
Unknown 1 7%
Readers by discipline Count As %
Agricultural and Biological Sciences 6 40%
Biochemistry, Genetics and Molecular Biology 2 13%
Computer Science 2 13%
Physics and Astronomy 1 7%
Decision Sciences 1 7%
Other 1 7%
Unknown 2 13%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 November 2014.
All research outputs
#22,758,309
of 25,373,627 outputs
Outputs from BMC Genomics
#9,840
of 11,244 outputs
Outputs of similar age
#281,383
of 320,960 outputs
Outputs of similar age from BMC Genomics
#174
of 204 outputs
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