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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Quantifying the intensity of permethrin insecticide resistance in Anopheles mosquitoes in western Kenya
|
|---|---|
| Published in |
Parasites & Vectors, November 2017
|
| DOI | 10.1186/s13071-017-2489-6 |
| Pubmed ID | |
| Authors |
Seline Omondi, Wolfgang Richard Mukabana, Eric Ochomo, Margaret Muchoki, Brigid Kemei, Charles Mbogo, Nabie Bayoh |
| Abstract |
The development and spread of resistance among local vectors to the major classes of insecticides used in Long-Lasting Insecticidal Nets (LLINs) and Indoor Residual Spraying (IRS) poses a major challenge to malaria vector control programs worldwide. The main methods of evaluating insecticide resistance in malaria vectors are the WHO tube bioassay and CDC bottle assays, with their weakness being determination of resistance at a fixed dose for variable populations. The CDC bottle assay using different insecticide dosages has proved applicable in ascertaining the intensity of resistance. We determined the status and intensity of permethrin resistance and investigated the efficacy of commonly used LLINs (PermaNet® 2.0, PermaNet® 3.0 and Olyset®) against 3-5 day-old adult female Anopheles mosquitoes from four sub-counties; Teso, Bondo, Rachuonyo and Nyando in western Kenya. Knockdown was assessed to 4 doses of permethrin; 1× (21.5 μg/ml), 2× (43 μg/ml), 5× (107.5 μg/ml) and 10× (215 μg/ml) using CDC bottle assays. Mortality for 0.75% permethrin ranged from 23.5% to 96.1% in the WHO tube assay. Intensity of permethrin resistance was highest in Barkanyango Bondo, with 84% knockdown at the 30 min diagnostic time when exposed to the 10× dose. When exposed to the LLINs, mortality ranged between- 0-39% for Olyset®, 12-88% for PermaNet® 2.0 and 26-89% for PermaNet® 3.0. The efficacy of nets was reduced in Bondo and Teso. Results from this study show that there was confirmed resistance in all the sites; however, intensity assays were able to differentiate Bondo and Teso as the sites with the highest levels of resistance, which coincidentally were the two sub-counties with reduced net efficacy. There was a reduced efficacy of nets in areas with high resistance portraying that at certain intensities of resistance, vector control using LLINs may be compromised. It is necessary to incorporate intensity assays in order to determine the extent of threat that resistance poses to malaria control. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Germany | 1 | 50% |
| Unknown | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 71 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 71 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 13 | 18% |
| Researcher | 13 | 18% |
| Student > Postgraduate | 8 | 11% |
| Student > Ph. D. Student | 7 | 10% |
| Lecturer | 3 | 4% |
| Other | 6 | 8% |
| Unknown | 21 | 30% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 12 | 17% |
| Medicine and Dentistry | 9 | 13% |
| Nursing and Health Professions | 5 | 7% |
| Environmental Science | 5 | 7% |
| Biochemistry, Genetics and Molecular Biology | 3 | 4% |
| Other | 12 | 17% |
| Unknown | 25 | 35% |
Attention Score in Context
This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 July 2020.
All research outputs
#6,865,735
of 23,007,887 outputs
Outputs from Parasites & Vectors
#1,560
of 5,502 outputs
Outputs of similar age
#112,996
of 330,783 outputs
Outputs of similar age from Parasites & Vectors
#52
of 154 outputs
Altmetric has tracked 23,007,887 research outputs across all sources so far. This one has received more attention than most of these and is in the 69th percentile.
So far Altmetric has tracked 5,502 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.7. This one has gotten more attention than average, scoring higher than 70% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 330,783 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 65% of its contemporaries.
We're also able to compare this research output to 154 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 66% of its contemporaries.