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Title |
Ion Prostate Irradiation (IPI) – a pilot study to establish the safety and feasibility of primary hypofractionated irradiation of the prostate with protons and carbon ions in a raster scan technique
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Published in |
BMC Cancer, March 2014
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DOI | 10.1186/1471-2407-14-202 |
Pubmed ID | |
Authors |
Gregor Habl, Gencay Hatiboglu, Lutz Edler, Matthias Uhl, Sonja Krause, Matthias Roethke, Heinz P Schlemmer, Boris Hadaschik, Juergen Debus, Klaus Herfarth |
Abstract |
Due to physical characteristics, ions like protons or carbon ions can administer the dose to the target volume more efficiently than photons since the dose can be lowered at the surrounding normal tissue. Radiation biological considerations are based on the assumption that the α/β value for prostate cancer cells is 1.5 Gy, so that a biologically more effective dose could be administered due to hypofractionation without increasing risks of late effects of bladder (α/β = 4.0) and rectum (α/β = 3.9). |
Mendeley readers
The data shown below were compiled from readership statistics for 64 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
Germany | 1 | 2% |
Italy | 1 | 2% |
Unknown | 62 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 10 | 16% |
Other | 6 | 9% |
Student > Master | 5 | 8% |
Student > Doctoral Student | 5 | 8% |
Student > Bachelor | 4 | 6% |
Other | 16 | 25% |
Unknown | 18 | 28% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 12 | 19% |
Nursing and Health Professions | 6 | 9% |
Physics and Astronomy | 6 | 9% |
Computer Science | 3 | 5% |
Agricultural and Biological Sciences | 2 | 3% |
Other | 11 | 17% |
Unknown | 24 | 38% |