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Ion Prostate Irradiation (IPI) – a pilot study to establish the safety and feasibility of primary hypofractionated irradiation of the prostate with protons and carbon ions in a raster scan technique

Overview of attention for article published in BMC Cancer, March 2014
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Title
Ion Prostate Irradiation (IPI) – a pilot study to establish the safety and feasibility of primary hypofractionated irradiation of the prostate with protons and carbon ions in a raster scan technique
Published in
BMC Cancer, March 2014
DOI 10.1186/1471-2407-14-202
Pubmed ID
Authors

Gregor Habl, Gencay Hatiboglu, Lutz Edler, Matthias Uhl, Sonja Krause, Matthias Roethke, Heinz P Schlemmer, Boris Hadaschik, Juergen Debus, Klaus Herfarth

Abstract

Due to physical characteristics, ions like protons or carbon ions can administer the dose to the target volume more efficiently than photons since the dose can be lowered at the surrounding normal tissue. Radiation biological considerations are based on the assumption that the α/β value for prostate cancer cells is 1.5 Gy, so that a biologically more effective dose could be administered due to hypofractionation without increasing risks of late effects of bladder (α/β = 4.0) and rectum (α/β = 3.9).

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 64 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Germany 1 2%
Italy 1 2%
Unknown 62 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 10 16%
Other 6 9%
Student > Master 5 8%
Student > Doctoral Student 5 8%
Student > Bachelor 4 6%
Other 16 25%
Unknown 18 28%
Readers by discipline Count As %
Medicine and Dentistry 12 19%
Nursing and Health Professions 6 9%
Physics and Astronomy 6 9%
Computer Science 3 5%
Agricultural and Biological Sciences 2 3%
Other 11 17%
Unknown 24 38%