Title |
Missing value imputation for microarray data: a comprehensive comparison study and a web tool
|
---|---|
Published in |
BMC Systems Biology, December 2013
|
DOI | 10.1186/1752-0509-7-s6-s12 |
Pubmed ID | |
Authors |
Chia-Chun Chiu, Shih-Yao Chan, Chung-Ching Wang, Wei-Sheng Wu |
Abstract |
Microarray data are usually peppered with missing values due to various reasons. However, most of the downstream analyses for microarray data require complete datasets. Therefore, accurate algorithms for missing value estimation are needed for improving the performance of microarray data analyses. Although many algorithms have been developed, there are many debates on the selection of the optimal algorithm. The studies about the performance comparison of different algorithms are still incomprehensive, especially in the number of benchmark datasets used, the number of algorithms compared, the rounds of simulation conducted, and the performance measures used. |
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Researcher | 8 | 19% |
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Other | 3 | 7% |
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Other | 3 | 7% |
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Medicine and Dentistry | 3 | 7% |
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