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DNAVaxDB: the first web-based DNA vaccine database and its data analysis

Overview of attention for article published in BMC Bioinformatics, March 2014
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Good Attention Score compared to outputs of the same age (77th percentile)
  • Good Attention Score compared to outputs of the same age and source (71st percentile)

Mentioned by

patent
1 patent
wikipedia
1 Wikipedia page

Citations

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19 Dimensions

Readers on

mendeley
49 Mendeley
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Title
DNAVaxDB: the first web-based DNA vaccine database and its data analysis
Published in
BMC Bioinformatics, March 2014
DOI 10.1186/1471-2105-15-s4-s2
Pubmed ID
Authors

Rebecca Racz, Xinna Li, Mukti Patel, Zuoshuang Xiang, Yongqun He

Abstract

Since the first DNA vaccine studies were done in the 1990s, thousands more studies have followed. Here we report the development and analysis of DNAVaxDB (http://www.violinet.org/dnavaxdb), the first publically available web-based DNA vaccine database that curates, stores, and analyzes experimentally verified DNA vaccines, DNA vaccine plasmid vectors, and protective antigens used in DNA vaccines. All data in DNAVaxDB are annotated from reliable resources, particularly peer-reviewed articles. Among over 140 DNA vaccine plasmids, some plasmids were more frequently used in one type of pathogen than others; for example, pCMVi-UB for G- bacterial DNA vaccines, and pCAGGS for viral DNA vaccines. Presently, over 400 DNA vaccines containing over 370 protective antigens from over 90 infectious and non-infectious diseases have been curated in DNAVaxDB. While extracellular and bacterial cell surface proteins and adhesin proteins were frequently used for DNA vaccine development, the majority of protective antigens used in Chlamydophila DNA vaccines are localized to the inner portion of the cell. The DNA vaccine priming, other vaccine boosting vaccination regimen has been widely used to induce protection against infection of different pathogens such as HIV. Parasitic and cancer DNA vaccines were also systematically analyzed. User-friendly web query and visualization interfaces are available in DNAVaxDB for interactive data search. To support data exchange, the information of DNA vaccines, plasmids, and protective antigens is stored in the Vaccine Ontology (VO). DNAVaxDB is targeted to become a timely and vital source of DNA vaccines and related data and facilitate advanced DNA vaccine research and development.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 49 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Japan 1 2%
Unknown 48 98%

Demographic breakdown

Readers by professional status Count As %
Researcher 9 18%
Student > Bachelor 9 18%
Student > Ph. D. Student 8 16%
Student > Master 6 12%
Other 5 10%
Other 7 14%
Unknown 5 10%
Readers by discipline Count As %
Agricultural and Biological Sciences 16 33%
Biochemistry, Genetics and Molecular Biology 10 20%
Medicine and Dentistry 5 10%
Engineering 4 8%
Unspecified 2 4%
Other 7 14%
Unknown 5 10%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 February 2022.
All research outputs
#4,904,224
of 23,577,654 outputs
Outputs from BMC Bioinformatics
#1,853
of 7,400 outputs
Outputs of similar age
#47,743
of 224,855 outputs
Outputs of similar age from BMC Bioinformatics
#27
of 95 outputs
Altmetric has tracked 23,577,654 research outputs across all sources so far. Compared to these this one has done well and is in the 76th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 7,400 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.4. This one has gotten more attention than average, scoring higher than 73% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 224,855 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 77% of its contemporaries.
We're also able to compare this research output to 95 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 71% of its contemporaries.