Title |
Short versus long silver nanowires: a comparison of in vivo pulmonary effects post instillation
|
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Published in |
Particle and Fibre Toxicology, October 2014
|
DOI | 10.1186/s12989-014-0052-6 |
Pubmed ID | |
Authors |
Rona M Silva, Jingyi Xu, Clare Saiki, Donald S Anderson, Lisa M Franzi, Chris D Vulpe, Benjamin Gilbert, Laura S Van Winkle, Kent E Pinkerton |
Abstract |
Silver nanowires (Ag NWs) are increasingly being used to produce touchscreens for smart phones and computers. When applied in a thin film over a plastic substrate, Ag NWs create a transparent, highly-conductive network of fibers enabling the touch interface between consumers and their electronics. Large-scale application methods utilize techniques whereby Ag NW suspensions are deposited onto substrates via droplets. Aerosolized droplets increase risk of occupational Ag NW exposure. Currently, there are few published studies on Ag NW exposure-related health effects. Concerns have risen about the potential for greater toxicity from exposure to high-aspect ratio nanomaterials compared to their non-fibrous counterparts. This study examines whether Ag NWs of varying lengths affect biological responses and silver distribution within the lungs at different time-points. |
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