Title |
A case of radiation-induced osteosarcoma treated effectively by boron neutron capture therapy
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Published in |
Radiation Oncology, November 2014
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DOI | 10.1186/s13014-014-0237-z |
Pubmed ID | |
Authors |
Gen Futamura, Shinji Kawabata, Hiroyuki Siba, Toshihiko Kuroiwa, Minoru Suzuki, Natsuko Kondo, Koji Ono, Yoshinori Sakurai, Minoru Tanaka, Tomoki Todo, Shin-Ichi Miyatake |
Abstract |
We treated a 54-year-old Japanese female with a recurrent radiation-induced osteosarcoma arising from left occipital skull, by reactor-based boron neutron capture therapy (BNCT). Her tumor grew rapidly with subcutaneous and epidural extension. She eventually could not walk because of cerebellar ataxia. The tumor was inoperable and radioresistant. BNCT showed a marked initial therapeutic effect: the subcutaneous/epidural tumor reduced without radiation damage of the scalp except hair loss and the patient could walk again only 3 weeks after BNCT. BNCT seems to be a safe and very effective modality in the management of radiation-induced osteosarcomas that are not eligible for operation and other treatment modalities. |
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