Title |
Dynamic protein interaction modules in human hepatocellular carcinoma progression
|
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Published in |
BMC Systems Biology, December 2013
|
DOI | 10.1186/1752-0509-7-s5-s2 |
Pubmed ID | |
Authors |
Hui Yu, Chen-Ching Lin, Yuan-Yuan Li, Zhongming Zhao |
Abstract |
Gene expression profiles have been frequently integrated with the human protein interactome to uncover functional modules under specific conditions like disease state. Beyond traditional differential expression analysis, differential co-expression analysis has emerged as a robust approach to reveal condition-specific network modules, with successful applications in a few human disease studies. Hepatocellular carcinoma (HCC), which is often interrelated with the Hepatitis C virus, typically develops through multiple stages. A comprehensive investigation of HCC progression-specific differential co-expression modules may advance our understanding of HCC's pathophysiological mechanisms. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United States | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 23 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 6 | 26% |
Student > Postgraduate | 5 | 22% |
Student > Ph. D. Student | 5 | 22% |
Student > Master | 3 | 13% |
Lecturer | 1 | 4% |
Other | 1 | 4% |
Unknown | 2 | 9% |
Readers by discipline | Count | As % |
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Agricultural and Biological Sciences | 9 | 39% |
Immunology and Microbiology | 5 | 22% |
Biochemistry, Genetics and Molecular Biology | 2 | 9% |
Medicine and Dentistry | 2 | 9% |
Nursing and Health Professions | 1 | 4% |
Other | 2 | 9% |
Unknown | 2 | 9% |