Title |
A novel approach for multi-domain and multi-gene family identification provides insights into evolutionary dynamics of disease resistance genes in core eudicot plants
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Published in |
BMC Genomics, November 2014
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DOI | 10.1186/1471-2164-15-966 |
Pubmed ID | |
Authors |
Johannes A Hofberger, Beifei Zhou, Haibao Tang, Jonathan DG Jones, M Eric Schranz |
Abstract |
Recent advances in DNA sequencing techniques resulted in more than forty sequenced plant genomes representing a diverse set of taxa of agricultural, energy, medicinal and ecological importance. However, gene family curation is often only inferred from DNA sequence homology and lacks insights into evolutionary processes contributing to gene family dynamics. In a comparative genomics framework, we integrated multiple lines of evidence provided by gene synteny, sequence homology and protein-based Hidden Markov Modelling to extract homologous super-clusters composed of multi-domain resistance (R)-proteins of the NB-LRR type (for NUCLEOTIDE BINDING/LEUCINE-RICH REPEATS), that are involved in plant innate immunity. |
X Demographics
Geographical breakdown
Country | Count | As % |
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South Africa | 1 | 50% |
Unknown | 1 | 50% |
Demographic breakdown
Type | Count | As % |
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Scientists | 1 | 50% |
Members of the public | 1 | 50% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Germany | 2 | 2% |
United States | 1 | 1% |
Unknown | 86 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 26 | 29% |
Researcher | 21 | 24% |
Professor > Associate Professor | 7 | 8% |
Student > Master | 6 | 7% |
Student > Bachelor | 5 | 6% |
Other | 14 | 16% |
Unknown | 10 | 11% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 49 | 55% |
Biochemistry, Genetics and Molecular Biology | 17 | 19% |
Computer Science | 2 | 2% |
Engineering | 2 | 2% |
Environmental Science | 1 | 1% |
Other | 4 | 4% |
Unknown | 14 | 16% |