↓ Skip to main content

Antibiotic-free segregational plasmid stabilization in Escherichia coli owing to the knockout of triosephosphate isomerase (tpiA)

Overview of attention for article published in Microbial Cell Factories, April 2014
Altmetric Badge

About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (80th percentile)
  • High Attention Score compared to outputs of the same age and source (87th percentile)

Mentioned by

news
1 news outlet

Citations

dimensions_citation
31 Dimensions

Readers on

mendeley
78 Mendeley
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
Antibiotic-free segregational plasmid stabilization in Escherichia coli owing to the knockout of triosephosphate isomerase (tpiA)
Published in
Microbial Cell Factories, April 2014
DOI 10.1186/1475-2859-13-58
Pubmed ID
Authors

Ram Shankar Velur Selvamani, Maurice Telaar, Karl Friehs, Erwin Flaschel

Abstract

Segregational stability of plasmids is of major concern for recombinant bacterial production strains. One of the best strategies to counteract plasmid loss is the use of auxotrophic mutants which are complemented with the lacking gene along with the product-relevant ones. However, these knockout mutants often show unwanted growth in complex standard media or no growth at all under uncomplemented conditions. This led to the choice of a gene for knockout that only connects two essential arms of an essential metabolic pathway - the glycolysis.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 78 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Lithuania 1 1%
Unknown 77 99%

Demographic breakdown

Readers by professional status Count As %
Researcher 15 19%
Student > Ph. D. Student 13 17%
Student > Master 12 15%
Student > Bachelor 10 13%
Student > Postgraduate 5 6%
Other 10 13%
Unknown 13 17%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 24 31%
Agricultural and Biological Sciences 23 29%
Chemical Engineering 4 5%
Medicine and Dentistry 3 4%
Engineering 3 4%
Other 8 10%
Unknown 13 17%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 7. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 November 2014.
All research outputs
#4,167,289
of 22,770,070 outputs
Outputs from Microbial Cell Factories
#225
of 1,595 outputs
Outputs of similar age
#41,460
of 226,807 outputs
Outputs of similar age from Microbial Cell Factories
#2
of 16 outputs
Altmetric has tracked 22,770,070 research outputs across all sources so far. Compared to these this one has done well and is in the 80th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,595 research outputs from this source. They receive a mean Attention Score of 4.4. This one has done well, scoring higher than 84% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 226,807 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 80% of its contemporaries.
We're also able to compare this research output to 16 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 87% of its contemporaries.