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X Demographics
Mendeley readers
Attention Score in Context
| Title |
The overlap between vascular disease and Alzheimer’s disease - lessons from pathology
|
|---|---|
| Published in |
BMC Medicine, November 2014
|
| DOI | 10.1186/s12916-014-0206-2 |
| Pubmed ID | |
| Authors |
Johannes Attems, Kurt A Jellinger |
| Abstract |
Recent epidemiological and clinico-pathological data indicate considerable overlap between cerebrovascular disease (CVD) and Alzheimer's disease (AD) and suggest additive or synergistic effects of both pathologies on cognitive decline. The most frequent vascular pathologies in the aging brain and in AD are cerebral amyloid angiopathy and small vessel disease. Up to 84% of aged subjects show morphological substrates of CVD in addition to AD pathology. AD brains with minor CVD, similar to pure vascular dementia, show subcortical vascular lesions in about two-thirds, while in mixed type dementia (AD plus vascular dementia), multiple larger infarcts are more frequent. Small infarcts in patients with full-blown AD have no impact on cognitive decline but are overwhelmed by the severity of Alzheimer pathology, while in early stages of AD, cerebrovascular lesions may influence and promote cognitive impairment, lowering the threshold for clinically overt dementia. Further studies are warranted to elucidate the many hitherto unanswered questions regarding the overlap between CVD and AD as well as the impact of both CVD and AD pathologies on the development and progression of dementia. |
X Demographics
The data shown below were collected from the profiles of 7 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 29% |
| Sweden | 1 | 14% |
| United Kingdom | 1 | 14% |
| Unknown | 3 | 43% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 4 | 57% |
| Practitioners (doctors, other healthcare professionals) | 2 | 29% |
| Scientists | 1 | 14% |
Mendeley readers
The data shown below were compiled from readership statistics for 499 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Sweden | 1 | <1% |
| United Kingdom | 1 | <1% |
| Canada | 1 | <1% |
| Denmark | 1 | <1% |
| United States | 1 | <1% |
| Unknown | 494 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 80 | 16% |
| Researcher | 69 | 14% |
| Student > Master | 59 | 12% |
| Student > Bachelor | 53 | 11% |
| Other | 27 | 5% |
| Other | 83 | 17% |
| Unknown | 128 | 26% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 93 | 19% |
| Neuroscience | 79 | 16% |
| Psychology | 42 | 8% |
| Agricultural and Biological Sciences | 41 | 8% |
| Biochemistry, Genetics and Molecular Biology | 29 | 6% |
| Other | 59 | 12% |
| Unknown | 156 | 31% |
Attention Score in Context
This research output has an Altmetric Attention Score of 20. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 February 2023.
All research outputs
#1,848,645
of 25,632,496 outputs
Outputs from BMC Medicine
#1,296
of 4,066 outputs
Outputs of similar age
#20,738
of 271,820 outputs
Outputs of similar age from BMC Medicine
#29
of 85 outputs
Altmetric has tracked 25,632,496 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 92nd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,066 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 45.1. This one has gotten more attention than average, scoring higher than 68% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 271,820 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 92% of its contemporaries.
We're also able to compare this research output to 85 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 65% of its contemporaries.