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The value of glucocorticoid co-therapy in different rheumatic diseases - positive and adverse effects

Overview of attention for article published in Arthritis Research & Therapy, November 2014
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Good Attention Score compared to outputs of the same age (79th percentile)
  • Good Attention Score compared to outputs of the same age and source (68th percentile)

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Citations

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272 Mendeley
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Title
The value of glucocorticoid co-therapy in different rheumatic diseases - positive and adverse effects
Published in
Arthritis Research & Therapy, November 2014
DOI 10.1186/ar4686
Pubmed ID
Authors

Marlies C van der Goes, Johannes W Jacobs, Johannes W Bijlsma

Abstract

Glucocorticoids play a pivotal role in the management of many inflammatory rheumatic diseases. The therapeutic effects range from pain relief in arthritides, to disease-modifying effects in early rheumatoid arthritis, and to strong immunosuppressive actions in vasculitides and systemic lupus erythematosus. There are multiple indications that adverse effects are more frequent with the longer use of glucocorticoids and use of higher dosages, but high-quality data on the occurrence of adverse effects are scarce especially for dosages above 10 mg prednisone daily. The underlying rheumatic disease, disease activity, risk factors and individual responsiveness of the patient should guide treatment decisions. Monitoring for adverse effects should also be tailored to the patient. Continuously balancing the benefits and risks of glucocorticoid therapy is recommended. There is an ongoing quest for new drugs with glucocorticoid actions without the potential to cause harmful effects, such as selective glucocorticoid receptor agonists, but the application of a new compound in clinical practice will probably not occur within the next few years. In the meantime, basic research on glucocorticoid effects and detailed reports on therapeutic efficacy and occurrence of adverse effects will be valuable in weighing benefits and risks in clinical practice.

X Demographics

X Demographics

The data shown below were collected from the profiles of 10 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 272 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 <1%
Canada 1 <1%
Unknown 269 99%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 43 16%
Student > Master 30 11%
Researcher 29 11%
Other 20 7%
Student > Ph. D. Student 20 7%
Other 56 21%
Unknown 74 27%
Readers by discipline Count As %
Medicine and Dentistry 100 37%
Biochemistry, Genetics and Molecular Biology 20 7%
Pharmacology, Toxicology and Pharmaceutical Science 18 7%
Agricultural and Biological Sciences 11 4%
Immunology and Microbiology 9 3%
Other 30 11%
Unknown 84 31%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 7. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 February 2017.
All research outputs
#5,227,130
of 25,373,627 outputs
Outputs from Arthritis Research & Therapy
#1,227
of 3,381 outputs
Outputs of similar age
#56,266
of 270,389 outputs
Outputs of similar age from Arthritis Research & Therapy
#18
of 58 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. Compared to these this one has done well and is in the 79th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,381 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.2. This one has gotten more attention than average, scoring higher than 63% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 270,389 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 79% of its contemporaries.
We're also able to compare this research output to 58 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 68% of its contemporaries.