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Photodynamic therapy as a novel treatment for halitosis in adolescents: study protocol for a randomized controlled trial

Overview of attention for article published in Trials, November 2014
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Title
Photodynamic therapy as a novel treatment for halitosis in adolescents: study protocol for a randomized controlled trial
Published in
Trials, November 2014
DOI 10.1186/1745-6215-15-443
Pubmed ID
Authors

Rubia Garcia Lopes, Camila Haddad Leal de Godoy, Alessandro Melo Deana, Maria Eugenia Simões Onofre de Santi, Renato Araujo Prates, Cristiane Miranda França, Kristianne Porta Santos Fernandes, Raquel Agnelli Mesquita-Ferrari, Sandra Kalil Bussadori

Abstract

Halitosis is a common problem that affects a large portion of the population worldwide. The origin of this condition is oral in 90% and systemic in 10% of cases. The unpleasant odor is mainly the result of volatile sulfur compounds produced by Gram-negative bacteria. However, it has recently been found that anaerobic Gram-positive bacteria also produce hydrogen sulfide (H2S) in the presence of amino acids, such as cysteine. Light, both with and without the use of chemical agents, has been used to induce therapeutic and antimicrobial effects. In photodynamic therapy, the antimicrobial effect is confined to areas covered by photosensitizing dye. The aim of the present study is to evaluate the antimicrobial effect of photodynamic therapy on halitosis in adolescents through the analysis of volatile sulfur compounds measured using gas chromatography and microbiological analysis of coated tongue.

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Mendeley readers

The data shown below were compiled from readership statistics for 86 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 86 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 13 15%
Student > Master 13 15%
Student > Bachelor 12 14%
Researcher 8 9%
Other 5 6%
Other 11 13%
Unknown 24 28%
Readers by discipline Count As %
Medicine and Dentistry 37 43%
Agricultural and Biological Sciences 6 7%
Nursing and Health Professions 3 3%
Biochemistry, Genetics and Molecular Biology 3 3%
Pharmacology, Toxicology and Pharmaceutical Science 2 2%
Other 9 10%
Unknown 26 30%