Title |
Photodynamic therapy as a novel treatment for halitosis in adolescents: study protocol for a randomized controlled trial
|
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Published in |
Trials, November 2014
|
DOI | 10.1186/1745-6215-15-443 |
Pubmed ID | |
Authors |
Rubia Garcia Lopes, Camila Haddad Leal de Godoy, Alessandro Melo Deana, Maria Eugenia Simões Onofre de Santi, Renato Araujo Prates, Cristiane Miranda França, Kristianne Porta Santos Fernandes, Raquel Agnelli Mesquita-Ferrari, Sandra Kalil Bussadori |
Abstract |
Halitosis is a common problem that affects a large portion of the population worldwide. The origin of this condition is oral in 90% and systemic in 10% of cases. The unpleasant odor is mainly the result of volatile sulfur compounds produced by Gram-negative bacteria. However, it has recently been found that anaerobic Gram-positive bacteria also produce hydrogen sulfide (H2S) in the presence of amino acids, such as cysteine. Light, both with and without the use of chemical agents, has been used to induce therapeutic and antimicrobial effects. In photodynamic therapy, the antimicrobial effect is confined to areas covered by photosensitizing dye. The aim of the present study is to evaluate the antimicrobial effect of photodynamic therapy on halitosis in adolescents through the analysis of volatile sulfur compounds measured using gas chromatography and microbiological analysis of coated tongue. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Scientists | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 86 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 13 | 15% |
Student > Master | 13 | 15% |
Student > Bachelor | 12 | 14% |
Researcher | 8 | 9% |
Other | 5 | 6% |
Other | 11 | 13% |
Unknown | 24 | 28% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 37 | 43% |
Agricultural and Biological Sciences | 6 | 7% |
Nursing and Health Professions | 3 | 3% |
Biochemistry, Genetics and Molecular Biology | 3 | 3% |
Pharmacology, Toxicology and Pharmaceutical Science | 2 | 2% |
Other | 9 | 10% |
Unknown | 26 | 30% |